Landscape of internal N7-methylguanosine of long non-coding RNA modifications in resistant acute myeloid leukemia

J Han, Q Liu, Y Zhou, D Li, R Wang - BMC genomics, 2023 - Springer
Background Growing evidence indicates that RNA methylation plays a fundamental role in
epigenetic regulation, which is associated with the tumorigenesis and drug resistance …

Transcriptome profiling of N7-methylguanosine modification of messenger RNA in drug-resistant acute myeloid leukemia

B Zhang, D Li, R Wang - Frontiers in oncology, 2022 - frontiersin.org
Acute myeloid leukemia (AML) is an aggressive hematological tumor caused by the
malignant transformation of myeloid progenitor cells. Although intensive chemotherapy …

Transcriptome-Wide Analysis of RNA N6-Methyladenosine Modification in Adriamycin-Resistant Acute Myeloid Leukemia Cells

S Fang, B Peng, Y Wen, J Yang, H Wang… - Frontiers in …, 2022 - frontiersin.org
Acute myeloid leukemia (AML) is one of the most aggressive hematopoietic malignancies.
Patients still suffer from refractory/relapsed disease after anthracycline-based therapy, which …

Integrated analysis of single-cell RNA-seq and bulk RNA-seq reveals RNA N6-methyladenosine modification associated with prognosis and drug resistance in acute …

Z Li, X Liu, L Wang, H Zhao, S Wang, G Yu… - Frontiers in …, 2023 - frontiersin.org
Introduction Acute myeloid leukemia (AML) is a type of blood cancer that is identified by the
unrestricted growth of immature myeloid cells within the bone marrow. Despite therapeutic …

N6-methyladenosine methylation analysis of long noncoding RNAs and mRNAs in 5-FU-resistant colon cancer cells

J Lai, Z Zhou, K Hu, HL Yu, X Su, X Niu, H Li, S Mao - Epigenetics, 2024 - Taylor & Francis
ABSTRACT N6 methyladenosine (m6A), methylation at the sixth N atom of adenosine, is the
most common and abundant modification in mammalian mRNAs and non-coding RNAs …

RNA N6-methyladenosine reader IGF2BP3 promotes acute myeloid leukemia progression by controlling stabilization of EPOR mRNA

J Fan, M Zhuang, W Fan, M Hou - PeerJ, 2023 - peerj.com
Background N6-methyladenosine (m6A) methylation epigenetically regulates normal
hematopoiesis and plays a role in the pathogenesis of acute myeloid leukemia (AML) …

Functions of RNA N6-methyladenosine modification in acute myeloid leukemia

X Zheng, Y Gong - Biomarker Research, 2021 - Springer
Acute myeloid leukemia (AML) is a hematologic malignancy with an unfavorable prognosis.
A better understanding of AML pathogenesis and chemotherapy resistance at the molecular …

Dynamic alterations of the transcriptome-wide m6A methylome in cytogenetically normal acute myeloid leukaemia during initial diagnosis and relapse

J Zhang, T Liu, Y Wang, X Yan, Y Li, F Xu, R Zhang - Genomics, 2023 - Elsevier
Accumulating studies have indicated that N6-methyladenosine (m 6 A) plays an important
role in acute myeloid leukaemia (AML). However, little is known about the m 6 A methylome …

N6-Methyladenosine-Related lncRNAs are novel prognostic markers and predict the immune landscape in acute myeloid leukemia

L Zhang, W Ke, P Hu, Z Li, W Geng, Y Guo… - Frontiers in …, 2022 - frontiersin.org
Background: Acute myelocytic leukemia (AML) is one of the hematopoietic cancers with an
unfavorable prognosis. However, the prognostic value of N 6-methyladenosine-associated …

[HTML][HTML] Analysis of m6A-related signatures associated with the tumor immune microenvironment and predict survival in acute myeloid leukemia

S Yuan, Z Cong, J Ji, L Zhu, Q Jiang… - Annals of …, 2022 - ncbi.nlm.nih.gov
Background Most previous studies have focused on the intrinsic carcinogenic pathways of
tumors; however, little is known about the potential role of N6-methyladenosine (m6A) …