Ageing of human skin may result from both the passage of time (intrinsic ageing) and from
cumulative exposure to external influences (extrinsic ageing) such as ultraviolet radiation …

Cutaneous ageing is the result of two distinct, biological processes which may occur
concurrently:(i) the passage of time, termed intrinsic ageing and (ii) environmental …

Cutaneous ageing is a complex biological phenomenon consisting of two components;
intrinsic ageing, which is largely genetically determined and extrinsic ageing caused by …

Photoageing of human skin due to chronic exposure to ultraviolet radiation (UVR) is
characterized histologically by extensive remodelling of the dermal elastic fibre system …

Skin is the most superficial body organ and plays an important role in protecting the body
from environmental damage and in forming social relations. With the increase of the aging …

Cutaneous aging is a complex biological phenomenon consisting of two distinct
components,(a) the intrinsic, genetically determined degenerative aging processes and (b) …

The aging process in the skin is complex and influenced by more intrinsic and extrinsic
factors than any other body organ. The effects of these two types of factors overlap for the …

Cutaneous aging represents a complex situation in which at least two independent factors—
innate aging and solar exposure—contribute to the development of degenerative changes in …

The dermis is primarily composed of the extracellular matrix (ECM) and fibroblasts. During
the aging process, the dermis undergoes significant changes. Collagen, which is a major …

Chronic sun exposure results in photoaged skin with deep coarse wrinkles and loss of
elasticity. We have examined the distribution and abundance of fibrillin-rich microfibrils, key …