[HTML][HTML] NCS-1 is a regulator of calcium signaling in health and disease

GR Boeckel, BE Ehrlich - Biochimica et Biophysica Acta (BBA)-Molecular …, 2018 - Elsevier
Abstract Neuronal Calcium Sensor-1 (NCS-1) is a highly conserved calcium binding protein
which contributes to the maintenance of intracellular calcium homeostasis and regulation of …

Current understanding of the role of neuronal calcium sensor 1 in neurological disorders

J Bandura, ZP Feng - Molecular Neurobiology, 2019 - Springer
Abstract Neuronal calcium sensor 1 (NCS-1) is a high-affinity calcium-binding protein and its
ubiquitous expression in the nervous system implies a wide range of functions. To date, it …

Neuronal calcium sensor-1 regulation of calcium channels, secretion, and neuronal outgrowth

JL Weiss, H Hui, RD Burgoyne - Cellular and molecular neurobiology, 2010 - Springer
Abstract Calcium (Ca 2+) is an important intracellular messenger underlying cell physiology.
Ca 2+ channels are the main entry route for Ca 2+ into excitable cells, and regulate …

[HTML][HTML] Neuronal calcium sensor 1 (NCS1) dependent modulation of neuronal morphology and development

TT Fischer, LD Nguyen, BE Ehrlich - FASEB journal: official …, 2021 - ncbi.nlm.nih.gov
Abstract Calcium (Ca2+) signaling is critical for neuronal functioning and requires the
concerted interplay of numerous Ca2+-binding proteins, including neuronal calcium sensor …

Calcium sensor, NCS-1, promotes tumor aggressiveness and predicts patient survival

LM Moore, A England, BE Ehrlich, DL Rimm - Molecular Cancer Research, 2017 - AACR
Abstract Neuronal Calcium Sensor 1 (NCS-1) is a multi-functional Ca2+-binding protein that
affects a range of cellular processes beyond those related to neurons. Functional …

Human neuronal calcium sensor-1 shows the highest expression level in cerebral cortex

C Chen, L Yu, P Zhang, J Jiang, Y Zhang, X Chen… - Neuroscience …, 2002 - Elsevier
Neuronal calcium sensors (NCS) are important constituents in the intracellular signaling
pathways. A novel human gene, NCS-1, was identified in the present study. Among the 16 …

Emerging Roles of Neuronal Ca2+ Sensor-1 in Cardiac and Neuronal Tissues: A Mini Review

TY Nakamura, S Nakao… - Frontiers in molecular …, 2019 - frontiersin.org
The EF-hand calcium (Ca2+)-binding protein, neuronal Ca2+ sensor-1 (NCS-1/frequenin), is
predominantly expressed in neuronal tissues and plays a crucial role in neuronal functions …

Neuronal calcium sensor-1: a multifunctional regulator of secretion

S Hilfiker - Biochemical Society Transactions, 2003 - portlandpress.com
Ca2+ ions play a crucial role not only as the trigger for neurotransmitter release, but also in
other aspects of brain function, such as short-term and long-term modulation of synaptic …

Functional status of neuronal calcium sensor-1 is modulated by zinc binding

PO Tsvetkov, AY Roman, VE Baksheeva… - Frontiers in Molecular …, 2018 - frontiersin.org
Neuronal calcium sensor-1 (NCS-1) protein is abundantly expressed in the central nervous
system and retinal neurons, where it regulates many vital processes such as synaptic …

Protection of neuronal calcium sensor 1 protein in cells treated with paclitaxel

JH Benbow, B DeGray, BE Ehrlich - Journal of Biological Chemistry, 2011 - ASBMB
Paclitaxel (Taxol) is one of the most effective treatment options for patients suffering from a
variety of cancers. A major side effect seen in a high percentage of patients treated with …