Although connections between cognitive deficits and age-associated brain differences have
been elucidated, relationships with motor performance are less well understood. Here, we …

Motor cognitive functions and their neurophysiology evolve and degrade along the lifespan
in a dramatic fashion. Current models of how the brain adapts to aging remain inspired …

The ability to inhibit actions, one of the hallmarks of human motor control, appears to decline
with advancing age. Evidence for a link between changes in inhibitory functions and poor …

Substantial evidence indicates that declines in cognitive and motor functioning are often
observed when we age. The interdependence of cognition and behavior has been reported …

Functional imaging studies have shown that seniors exhibit more elaborate brain activation
than younger controls while performing motor tasks. Here, we investigated whether this age …

Aging is associated with progressive losses in function across multiple systems, including
sensation, cognition, memory, motor control, and affect. The traditional view has been that …

We review four broad lines of research on couplings between sensorimotor and cognitive
aging, with an emphasis on methodological concerns. First, correlational cross-sectional …

Although functional imaging studies have frequently examined age-related changes in
neural recruitment during cognitive tasks, much less is known about such changes during …

Though the cortical contributions to age-related declines in motor and cognitive performance
are well-known, the potential contributions of the cerebellum are less clear. The diverse …

Highlights•Dopamine modulation declines in various brain regions during aging.•A
computational role of dopamine is neuronal gain control.•Aging neuronal gain control …