[HTML][HTML] ZEB1: catalyst of immune escape during tumor metastasis
J Lu, F Fei, C Wu, J Mei, J Xu, P Lu - Biomedicine & Pharmacotherapy, 2022 - Elsevier
The transcription factor zinc finger E-box binding homeobox 1 (ZEB1) is a critical inducer of
epithelial mesenchymal transformation (EMT) and plays a robust role in tumor metastasis. It …
epithelial mesenchymal transformation (EMT) and plays a robust role in tumor metastasis. It …
[HTML][HTML] Regulation of ZEB1 function and molecular associations in tumor progression and metastasis
M Perez-Oquendo, DL Gibbons - Cancers, 2022 - mdpi.com
Simple Summary Given the importance of the epithelial-to-mesenchymal transition in tumor
progression and the pivotal role of ZEB1 as a transcriptional repressor during this process …
progression and the pivotal role of ZEB1 as a transcriptional repressor during this process …
[HTML][HTML] The roles of ZEB1 in tumorigenic progression and epigenetic modifications
Y Zhang, L Xu, A Li, X Han - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Highly expressed Zinc-finger E-box binding protein 1 (ZEB1) is significantly associated with
the malignancy of various cancers. Signal transduction and activation of ZEB1 play …
the malignancy of various cancers. Signal transduction and activation of ZEB1 play …
[HTML][HTML] Post-translational modification of ZEB family members in cancer progression
MK Park, H Lee, CH Lee - International Journal of Molecular Sciences, 2022 - mdpi.com
Post-translational modification (PTM), the essential regulatory mechanisms of proteins, play
essential roles in physiological and pathological processes. In addition, PTM functions in …
essential roles in physiological and pathological processes. In addition, PTM functions in …
The crucial role of ZEB2: from development to epithelial‐to‐mesenchymal transition and cancer complexity
Zinc finger E‐box binding homeobox 2 (ZEB2) is a DNA‐binding transcription factor, which
is mainly involved in epithelial‐to‐mesenchymal transition (EMT). EMT is a conserved …
is mainly involved in epithelial‐to‐mesenchymal transition (EMT). EMT is a conserved …
[HTML][HTML] ZEB1: a critical regulator of cell plasticity, DNA damage response, and therapy resistance
The predominant way in which conventional chemotherapy kills rapidly proliferating cancer
cells is the induction of DNA damage. However, chemoresistance remains the main obstacle …
cells is the induction of DNA damage. However, chemoresistance remains the main obstacle …
ZEB1: at the crossroads of epithelial-mesenchymal transition, metastasis and therapy resistance
Zinc finger E-box binding homeobox 1 (ZEB1) is a transcription factor that promotes tumor
invasion and metastasis by inducing epithelial-mesenchymal transition (EMT) in carcinoma …
invasion and metastasis by inducing epithelial-mesenchymal transition (EMT) in carcinoma …
Effect of downregulation of ZEB1 on vimentin expression, tumour migration and tumourigenicity of melanoma B16F10 cells and CSCs
J Dou, X He, Y Liu, Y Wang, F Zhao… - Cell biology …, 2014 - Wiley Online Library
Zinc‐finger E‐box binding homeobox 1 (ZEB1) is a master regulator of epithelial‐
mesenchymal transition (EMT) and has been implicated in primary epithelial cancer …
mesenchymal transition (EMT) and has been implicated in primary epithelial cancer …
[HTML][HTML] ZEB1 transcription factor promotes immune escape in melanoma
M Plaschka, V Benboubker, M Grimont… - … for Immunotherapy of …, 2022 - ncbi.nlm.nih.gov
Background The efficacy of immunotherapies in metastatic melanoma depends on a robust
T cell infiltration. Oncogenic alterations of tumor cells have been associated to T cell …
T cell infiltration. Oncogenic alterations of tumor cells have been associated to T cell …
Role of ZEB family members in proliferation, metastasis, and chemoresistance of prostate cancer cells: revealing signaling networks
A Zarrabi, F Hashemi, F Hashemi… - Current cancer drug …, 2021 - ingentaconnect.com
Prostate cancer (PCa) is one of the leading causes of death worldwide. A variety of
strategies, including surgery, chemotherapy, radiotherapy, and immunotherapy, are applied …
strategies, including surgery, chemotherapy, radiotherapy, and immunotherapy, are applied …