Genetic risk for Huntington Disease and reproductive decision‐making: A systematic review

N Fahy, C Rice, N Lahiri, R Desai, J Stott - Clinical Genetics, 2023 - Wiley Online Library
Huntington Disease (HD) is an incurable autosomal dominant single gene
neurodegenerative disorder. Typical onset is between 30 and 40 years and characterised by …

Reproductive options for prospective parents in families with Huntington's disease: clinical, psychological and ethical reflections

CEM de Die-Smulders, G De Wert… - Human reproduction …, 2013 - academic.oup.com
BACKGROUND Huntington's disease (HD) is an autosomal dominant neurodegenerative
late onset disorder. This review of reproductive options aims to increase reproductive …

What were you thinking?: individuals at risk for Huntington disease talk about having children

KA Quaid, MM Swenson, SL Sims, JM Harrison… - Journal of Genetic …, 2010 - Springer
Most of the research on reproduction in those at risk for Huntington Disease (HD) has
focused on the impact of genetic testing on reproductive decision-making. The main goal …

Decision-making about reproductive choices among individuals at-risk for Huntington's disease

R Klitzman, D Thorne, J Williamson, W Chung… - Journal of Genetic …, 2007 - Springer
We explored how individuals at-risk for HD who have or have not been tested make
reproductive decisions and what factors are involved. We interviewed 21 individuals (8 with …

The complexity of reproductive decision-making in asymptomatic carriers of the Huntington mutation

M Decruyenaere, G Evers-Kiebooms… - European Journal of …, 2007 - nature.com
The aim of this study was to describe reproductive decisions in mutation carriers after
predictive testing for Huntington's disease (HD) and to identify factors that play a role in …

Reproductive decision making before and after predictive testing for Huntington's disease: an Australian perspective

FH Richards, G Rea - Clinical genetics, 2005 - Wiley Online Library
A retrospective study examined both pre‐and post‐result reproductive decision making for
281 people at risk for Huntington's disease aged 18–45 years who had undergone …

Predictive DNA-testing for Huntington's disease and reproductive decision making: a European collaborative study

G Evers-Kiebooms, K Nys, P Harper… - European journal of …, 2002 - nature.com
This European collaborative study addresses the question whether a predictive test result for
Huntington's disease (HD) has an effect on subsequent reproduction by comparing carriers …

The choice not to undergo genetic testing for Huntington disease: Results from the PHAROS study

KE Anderson, S Eberly, KS Marder, D Oakes… - Clinical …, 2019 - Wiley Online Library
Rates of genetic testing in Huntington disease (HD) are lower than was predicted before
direct DNA testing became available. Clinicians often do not have in‐depth conversations …

Genetic counselors' perceived responsibilities regarding reproductive issues for patients at risk for Huntington disease

KA Hines, P McCarthy Veach… - Journal of genetic …, 2010 - Wiley Online Library
Research indicates that health care professionals' attitudes may affect patients' decisions
regarding prenatal Huntington Disease testing, but few studies have sampled genetic …

Two decades of Huntington disease testing: patient's demographics and reproductive choices

RC Krukenberg, DL Koller, DD Weaver… - Journal of genetic …, 2013 - Wiley Online Library
Predictive testing for Huntington disease (HD) has been available in the United States (US)
since 1987, and the Indiana University Predictive Testing Program has been providing this …