Unpredictable chronic mild stress (UCMS) and developmental social isolation are often
utilized in laboratory animals to mimic unpredictable life stressors and early life adversity …

Chronic stress is the major pathogenetic factor of human anxiety and depression. Zebrafish
(Danio rerio) have become a novel popular model species for neuroscience research and …

Early-life stress can lead to two different behavioral responses:(1) increased susceptibility to
psychiatric disorders or (2) resilience. Here, we created a chronic unpredictable early-life …

Exposure to stress during early life affects subsequent behaviors and increases the
vulnerability to adult pathologies, a phenomenon that has been well documented in humans …

Zebrafish (Danio rerio) have emerged as a promising model organism to study
development, toxicology, pharmacology, and neuroscience, among other areas. Despite the …

In recent years, the zebrafish (Danio rerio) has become a popular model to study the
mechanisms of physiological and behavioral effects of stress, due to the similarity in neural …

Rationale Several model organisms have been employed to study the impacts of stress on
biological systems. Different models of unpredictable chronic stress (UCS) have been …

The zebrafish (Danio rerio) is emerging as a promising model organism for experimental
studies of stress and anxiety. Here we further validate zebrafish models of stress by …

Long-term recurrent stress is a common cause of neuropsychiatric disorders. Animal models
are widely used to study the pathogenesis of stress-related psychiatric disorders. The …

Experimental animal models are a valuable tool to study the neurobiology of emotional
behavior and mechanisms underlying human affective disorders. Mounting evidence …