[HTML][HTML] Inhibition of selenoprotein synthesis by Zika virus may contribute to congenital Zika syndrome and microcephaly by mimicking SELENOP knockout and the …

GP Dailey, LS Premadasa, JA Ruzicka, EW Taylor - BBA advances, 2021 - Elsevier
Selenium status plays a major role in health impacts of various RNA viruses. We previously
reported potential antisense interactions between viral mRNAs and host mRNAs encoding …

[PDF][PDF] Antisense inhibition of selenoprotein synthesis by Zika virus may contribute to neurological disorders and microcephaly by mimicking SePP1 knockout and the …

EW Taylor, JA Ruzicka - Bull World Health Organ, 2016 - core.ac.uk
Objective: Selenium status plays a major role in health impacts of various RNA viruses. We
recently reported potential antisense interactions between viral mRNAs and host mRNAs of …

[HTML][HTML] Dissecting the toxic effects of Zika virus proteins on neural progenitor cells

RO Ferreira, PP Garcez - Neuron, 2019 - cell.com
Dissecting the Toxic Effects of Zika Virus Proteins on Neural Progenitor Cells: Neuron Skip to
Main Content Advertisement Neuron This journal offers authors two options (open access or …

[HTML][HTML] Zika virus impairs neurogenesis and synaptogenesis pathways in human neural stem cells and neurons

L Rosa-Fernandes, FR Cugola, FB Russo… - Frontiers in cellular …, 2019 - frontiersin.org
Growing evidences have associated Zika virus (ZIKV) infection with congenital
malformations, including microcephaly. Nonetheless, signaling mechanisms that promote …

Zika virus and neural developmental defects: building a case for a cause

SC Ogden, C Hammack, H Tang - Science China Life Sciences, 2016 - Springer
Zika virus (ZIKV), a little-known flavivirus until a few months ago, is currently at the forefront
of public health concerns worldwide because of its suspected role in causing microcephaly …

Molecular alterations in the extracellular matrix in the brains of newborns with congenital Zika syndrome

RS Aguiar, F Pohl, GL Morais, FCS Nogueira… - Science …, 2020 - science.org
Zika virus (ZIKV) infection during pregnancy can cause a set of severe abnormalities in the
fetus known as congenital Zika syndrome (CZS). Experiments with animal models and in …

Neurotoxic properties of the Zika virus envelope protein

JP Steiner, M Bachani, N Malik, W Li, R Tyagi… - Experimental …, 2023 - Elsevier
Prenatal Zika virus (ZIKV) infection is a serious global concern as it can lead to brain injury
and many serious birth defects, collectively known as congenital Zika syndrome. Brain injury …

[HTML][HTML] Zika virus NS4A and NS4B proteins deregulate Akt-mTOR signaling in human fetal neural stem cells to inhibit neurogenesis and induce autophagy

Q Liang, Z Luo, J Zeng, W Chen, SS Foo, SA Lee, J Ge… - Cell stem cell, 2016 - cell.com
The current widespread outbreak of Zika virus (ZIKV) infection has been linked to severe
clinical birth defects, particularly microcephaly, warranting urgent study of the molecular …

New candidate genes potentially involved in Zika virus teratogenesis

MF Maciel-Fiuza, BD Rengel, GE Wachholz… - Computers in Biology …, 2024 - Elsevier
Despite efforts to elucidate Zika virus (ZIKV) teratogenesis, still several issues remain
unresolved, particularly on the molecular mechanisms behind the pathogenesis of …

[PDF][PDF] RNA viruses vs. DNA synthesis: a general viral strategy that may contribute to the protective antiviral effects of selenium

EW Taylor - Preprints, 2020 - researchgate.net
The biosynthesis of DNA inherently competes with RNA synthesis because it depends on
the reduction 10 of ribonucleotides (RNA precursors) to 2'-deoxyribonucleotides by …