Peripheral nerve injury induces changes in the activity of inhibitory interneurons as visualized in transgenic Gad1-Gcamp6s rats
V Krishnan, LC Wade-Kleyn, RR Israeli, G Pelled - Biosensors, 2022 - mdpi.com
Peripheral nerve injury induces cortical remapping that can lead to sensory complications.
There is evidence that inhibitory interneurons play a role in this process, but the exact …
There is evidence that inhibitory interneurons play a role in this process, but the exact …
Spatial and temporal pattern of changes in the number of GAD65-immunoreactive inhibitory terminals in the rat superficial dorsal horn following peripheral nerve injury
LE Lorenzo, C Magnussen, AL Bailey… - Molecular …, 2014 - journals.sagepub.com
Inhibitory interneurons are an important component of dorsal horn circuitry where they serve
to modulate spinal nociception. There is now considerable evidence indicating that reduced …
to modulate spinal nociception. There is now considerable evidence indicating that reduced …
Interneuron subtypes enable independent modulation of excitatory and inhibitory firing rates after sensory deprivation
LMA Richter, J Gjorgjieva - BioRxiv, 2021 - biorxiv.org
Diverse interneuron subtypes determine how cortical circuits process sensory information
depending on their connectivity. Sensory deprivation experiments are ideally suited to …
depending on their connectivity. Sensory deprivation experiments are ideally suited to …
[HTML][HTML] Cellular and Molecular Properties of Neurons: Calcium homeostasis in parvalbumin DRG neurons is altered after sciatic nerve crush and sciatic nerve …
MC Walters, DR Ladle - Journal of Neurophysiology, 2021 - ncbi.nlm.nih.gov
Reflex abnormalities mediated by proprioceptive sensory neurons after peripheral nerve
injury (PNI) can limit functional improvement, leaving patients with disability that affects their …
injury (PNI) can limit functional improvement, leaving patients with disability that affects their …
Dysfunction of cortical GABAergic neurons leads to sensory hyper-reactivity in a Shank3 mouse model of ASD
Q Chen, CA Deister, X Gao, B Guo, T Lynn-Jones… - Nature …, 2020 - nature.com
Hyper-reactivity to sensory input is a common and debilitating symptom in individuals with
autism spectrum disorders (ASD), but the neural basis underlying sensory abnormality is not …
autism spectrum disorders (ASD), but the neural basis underlying sensory abnormality is not …
Acute inhibition of acid sensing ion channel 1a after spinal cord injury selectively affects excitatory synaptic transmission, but not intrinsic membrane properties, in …
Following a spinal cord injury (SCI), secondary damage mechanisms are triggered that
cause inflammation and cell death. A key component of this secondary damage is a …
cause inflammation and cell death. A key component of this secondary damage is a …
Dorsal horn CGRP-expressing interneurons contribute to nerve injury-induced mechanical hypersensitivity
LS Löken, A Etlin, M Bernstein, M Steyert, J Kuhn… - bioRxiv, 2020 - biorxiv.org
Primary sensory neurons are generally considered the only source of dorsal horn calcitonin
gene-related peptide (CGRP), a neuropeptide critical to the transmission of pain messages …
gene-related peptide (CGRP), a neuropeptide critical to the transmission of pain messages …
Loss of GABAergic interneurons in laminae I–III of the spinal cord dorsal horn contributes to reduced GABAergic tone and neuropathic pain after spinal cord injury
JG Meisner, AD Marsh, DR Marsh - Journal of neurotrauma, 2010 - liebertpub.com
In this study we explore if loss of GABAergic inhibitory interneurons in the superficial dorsal
horn of the spinal cord contributes to reduced GABAergic tone and neuropathic pain …
horn of the spinal cord contributes to reduced GABAergic tone and neuropathic pain …
Spinal cord injury causes plasticity in a subpopulation of lamina I GABAergic interneurons
KJ Dougherty, S Hochman - Journal of neurophysiology, 2008 - journals.physiology.org
Dysfunction of the spinal GABAergic system has been implicated in pain syndromes
following spinal cord injury (SCI). Since lamina I is involved in nociceptive and thermal …
following spinal cord injury (SCI). Since lamina I is involved in nociceptive and thermal …
Morphological and physiological plasticity of spinal lamina II GABA neurons is induced by sciatic nerve chronic constriction injury in mice
Mice with transgenic insertion of code for enhanced green fluorescent protein (EGFP) at the
locus for glutamic acid decarboxylase 67 (GAD67), one of two key enzymes for the synthesis …
locus for glutamic acid decarboxylase 67 (GAD67), one of two key enzymes for the synthesis …
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