Precision medicine relies on individually tailored therapeutic intervention taking into account
individual variability. It is strongly dependent on the availability of target-specific drugs …

G-Protein-coupled receptors (GPCRs) are ubiquitous within eukaryotes, responsible for a
wide array of physiological and pathological processes. Indeed, the fact that they are the …

Abstract Scientists Robert J. Lefkowitz and Brian K. Kobilka won the Nobel Prize in 2012 for
reporting a groundbreaking discovery that revealed a crucial member of the receptor family …

The growth hormone secretagogue receptor 1a (GHSR), also called the ghrelin receptor, is
a G protein-coupled receptor known to play an important metabolic role in the regulation of …

G-protein-coupled receptors (GPCRs) mediate many important physiological functions and
are considered as one of the most successful therapeutic targets for a broad spectrum of …

G-protein-coupled receptors (GPCRs) are the largest and most versatile cell surface
receptor family with a broad repertoire of ligands and functions. We've learned an enormous …

G-protein coupled receptors (GPCRs) represent important targets for drug discovery
because they participate in a wide range of cellular signalling pathways that play a role in a …

G protein-coupled receptors (GPCRs) remain a major domain of pharmaceutical discovery.
The identification of GPCR lead compounds and their optimization are now structure-based …

Positron emission tomography (PET) is a molecular imaging modality that enables in vivo
exploration of metabolic processes and especially the pharmacology of neuroreceptors. G …

The 2016 EANM Congress took place in Barcelona, Spain, from 15 to 19 October under the
leadership of Prof. Wim Oyen, chair of the EANM Scientific Committee. With more than 6,000 …