Beyond cholinesterase inhibition: developmental neurotoxicity of organophosphate ester flame retardants and plasticizers

HB Patisaul, M Behl, LS Birnbaum… - Environmental …, 2021 - ehp.niehs.nih.gov
Background: To date, the toxicity of organophosphate esters has primarily been studied
regarding their use as pesticides and their effects on the neurotransmitter …

Organophosphate esters: are these flame retardants and plasticizers affecting children's health?

BT Doherty, SC Hammel, JL Daniels… - Current environmental …, 2019 - Springer
Abstract Purpose of Review Organophosphate esters (OPEs) are applied to a variety of
consumer products, primarily as flame retardants and plasticizers. OPEs can leach out of …

Developmental exposure to organophosphate flame retardants causes behavioral effects in larval and adult zebrafish

AN Oliveri, JM Bailey, ED Levin - Neurotoxicology and teratology, 2015 - Elsevier
Abstract Background Organophosphate flame retardants (OPFRs) have grown in usage
since concerns about the health effects of the previously used polybrominated flame …

[HTML][HTML] Organophosphorus flame retardants are developmental neurotoxicants in a rat primary brainsphere in vitro model

HT Hogberg, R de Cássia da Silveira E Sá… - Archives of …, 2021 - Springer
Due to regulatory bans and voluntary substitutions, halogenated polybrominated diphenyl
ether (PBDE) flame retardants (FR) are increasingly substituted by mainly …

Effects of prenatal exposure to a mixture of organophosphate flame retardants on placental gene expression and serotonergic innervation in the fetal rat brain

KD Rock, G St Armour, B Horman… - Toxicological …, 2020 - academic.oup.com
There is a growing need to understand the potential neurotoxicity of organophosphate flame
retardants (OPFRs) and plasticizers because use and, consequently, human exposure, is …

[HTML][HTML] A systematic scoping review of epidemiological studies on the association between organophosphate flame retardants and neurotoxicity

J Zhao, Z Zhan, M Lu, F Tao, D Wu, H Gao - … and Environmental Safety, 2022 - Elsevier
Organophosphate flame retardants (OPFRs) are increasingly and widely used as substitutes
for brominated flame retardants in daily life. The chemical structure of OPFRs is very similar …

Guidelines for developmental neurotoxicity and their impact on organophosphate pesticides: a personal view from an academic perspective

TA Slotkin - Neurotoxicology, 2004 - Elsevier
The appropriate regulation of drugs, chemicals and environmental contaminants requires
the establishment of clear and accepted guidelines for developmental neurotoxicity. Ideally …

Use of alternative assays to identify and prioritize organophosphorus flame retardants for potential developmental and neurotoxicity

M Behl, JH Hsieh, TJ Shafer, WR Mundy… - Neurotoxicology and …, 2015 - Elsevier
Due to their toxicity and persistence in the environment, brominated flame retardants (BFRs)
are being phased out of commercial use, leading to the increased use of alternative …

Neurotoxicological and thyroid evaluations of rats developmentally exposed to tris (1, 3-dichloro-2-propyl) phosphate (TDCIPP) and tris (2-chloro-2-ethyl) phosphate …

VC Moser, PM Phillips, JM Hedge… - Neurotoxicology and …, 2015 - Elsevier
Abstract Tris (1, 3-dichloro-2-propyl) phosphate (TDCIPP) and tris (2-chloro-2-ethyl)
phosphate (TCEP) are organophosphorous flame retardants with widespread usage and …

Developmental exposure of zebrafish larvae to organophosphate flame retardants causes neurotoxicity

L Sun, W Xu, T Peng, H Chen, L Ren, H Tan… - Neurotoxicology and …, 2016 - Elsevier
With the gradual ban on brominated flame retardants (FRs), the application of
organophosphate flame retardants (OPFRs) has increased remarkably. Considering the …