Objective Insulinomas and non-functional pancreatic neuroendocrine tumours (NF-
PanNETs) have distinctive clinical presentations but share similar pathological features …

Neuroendocrine tumours (NETs) may arise throughout the body and are a highly
heterogeneous, relatively rare class of neoplasms difficult to study also for the lack of …

Pancreatic neuroendocrine tumors (pNETs) are uncommon cancers arising from pancreatic
islet cells. Here we report the analysis of gene mutation, copy number, and RNA expression …

Neuroendocrine neoplasms (NENs) are a relatively rare group of heterogeneous tumours
originating from neuroendocrine cells found throughout the body. Pancreatic NENs …

Metastatic and locally-advanced neuroendocrine neoplasms (aNEN) form clinically and
genetically heterogeneous malignancies, characterized by distinct prognoses based upon …

Abstract Background Pancreatic neuroendocrine neoplasms (PanNENs) fall into two
subclasses: the well-differentiated, low-to high-grade pancreatic neuroendocrine tumors …

The commonly mutated genes in pancreatic neuroendocrine tumors (PanNETs) are ATRX,
DAXX, and MEN1. We genotyped 64 PanNETs and found 58% carry ATRX, DAXX, and …

This review focuses on discussing the main modifications of the recently published 2017
WHO Classification of Neoplasms of the Neuroendocrine Pancreas (panNEN). Recent …

Purpose: GEP-NENs are rare malignancies with increasing incidence. Their molecular
characteristics are still undefined. We explored the underlying biology of GEP-NENs and the …

Gastroenteropancreatic (GEP) neuroendocrine neoplasms (NENs) are heterogeneous
regarding site of origin, biological behavior, and malignant potential. There has been a rapid …