Background Tauroursodeoxycholic acid (TUDCA) is a hydrophilic bile acid derivative, which
has been demonstrated to have neuroprotective effects in different neurological disease …

Traumatic brain injury (TBI) is one of the leading causes of trauma-induced mortality and
disability, and emerging studies have shown that endoplasmic reticulum (ER) stress plays …

The aim of this study was to investigate the anti-inflammatory effects by ursodeoxycholic acid
(UDCA) in rats with a spinal cord injury (SCI). A moderate mechanical compression injury …

This study aimed to investigate the anti-inflammatory effects of tauroursodeoxycholic acid
(TUDCA) after spinal cord injury (SCI) in rats. We induced an inflammatory process in RAW …

Background Bile acids are steroid acids found predominantly in the bile of mammals. The
bile acid conjugate tauroursodeoxycholic acid (TUDCA) is a neuroprotective agent in …

Greater clinical understanding of the pivotal role of apoptosis in spinal cord injury (SCI) has
led to new and innovative apoptosis-based therapies for patients with an SCI …

The objective of this review was to evaluate the potential of tauroursodeoxycholic acid
(TUDCA) for neuroprotection in traumatic brain injury (TBI) patients in the neurocritical care …

Accumulating evidence has shown that tauroursodeoxycholic acid (TUDCA) is
neuroprotective in different animal models of neurological diseases. However, whether …

The bile acid conjugate tauroursodeoxycholic acid (TUDCA) is a neuroprotective agent in
various animal models of neuropathologies. We have previously shown the anti …

Tauroursodeoxycholic acid (TUDCA), an endogenous bile acid, modulates cell death by
interrupting classic pathways of apoptosis. Intracerebral hemorrhage (ICH) is a devastating …