Journey of anthraquinones as anticancer agents–a systematic review of recent literature

MS Malik, RI Alsantali, RS Jassas, AA Alsimaree… - RSC …, 2021 - pubs.rsc.org
Anthraquinones are privileged chemical scaffolds that have been used for centuries in
various therapeutic applications. The anthraquinone moiety forms the core of various …

Novel anthraquinone compounds as anticancer agents and their potential mechanism

W Tian, C Wang, D Li, H Hou - Future medicinal chemistry, 2020 - Taylor & Francis
Anthraquinones exhibit a unique anticancer activity. Since their discovery, medicinal
chemists have made several structural modifications, resulting in the design and synthesis of …

Advances in the discovery of anthraquinone-based anticancer agents

AS Tikhomirov, AA Shtil… - Recent patents on anti …, 2018 - ingentaconnect.com
Background: The anthracene-9, 10-dione (anthraquinone) derivatives represent an
exceptionally valuable class in anticancer drug development. An outstanding antitumor …

Anthraquinone: a promising scaffold for the discovery and development of therapeutic agents in cancer therapy

S Siddamurthi, G Gutti, S Jana, A Kumar… - Future medicinal …, 2020 - Taylor & Francis
Cancer, characterized by uncontrolled malignant neoplasm, is a leading cause of death in
both advanced and emerging countries. Although, ample drugs are accessible in the market …

Navigating the synthesis of quinoline hybrid molecules as promising anticancer agents

P Panda, S Chakroborty - ChemistrySelect, 2020 - Wiley Online Library
The emergence of drug resistance and low specificity with side effects are the significant
challenges in pharmaceutical sectors for control of cancer nowadays. Notwithstanding, this …

Quinoline as a privileged scaffold in cancer drug discovery

VR Solomon, H Lee - Current medicinal chemistry, 2011 - ingentaconnect.com
Quinoline (1-azanaphthalene) is a heterocyclic aromatic nitrogen compound characterized
by a double-ring structure that contains a benzene ring fused to pyridine at two adjacent …

Anthraquinones as pharmacological tools and drugs

EM Malik, CE Müller - Medicinal research reviews, 2016 - Wiley Online Library
Abstract Anthraquinones (9, 10‐dioxoanthracenes) constitute an important class of natural
and synthetic compounds with a wide range of applications. Besides their utilization as …

Anthracycline and anthraquinone anticancer agents: current status and recent developments

JW Lown - Pharmacology & therapeutics, 1993 - Elsevier
The clinical treatment of neoplastic diseases relies on the complementary procedures of
surgery, radiation treatment, immunotherapy and chemotherapy. The latter technique has …

Quinolines, a perpetual, multipurpose scaffold in medicinal chemistry

P Yadav, K Shah - Bioorganic Chemistry, 2021 - Elsevier
Quinoline is a versatile pharmacophore, a privileged scaffold and an outstanding fused
heterocyclic compound with a wide range of pharmacological prospective such as …

Antitumour anthracyclines: progress and perspectives

MB Martins‐Teixeira, I Carvalho - ChemMedChem, 2020 - Wiley Online Library
Anthracyclines are ranked among the most effective chemotherapeutics against cancer.
They are glycoside drugs comprising the amino sugar daunosamine linked to a hydroxy …