Journey of anthraquinones as anticancer agents–a systematic review of recent literature
Anthraquinones are privileged chemical scaffolds that have been used for centuries in
various therapeutic applications. The anthraquinone moiety forms the core of various …
various therapeutic applications. The anthraquinone moiety forms the core of various …
Novel anthraquinone compounds as anticancer agents and their potential mechanism
W Tian, C Wang, D Li, H Hou - Future medicinal chemistry, 2020 - Taylor & Francis
Anthraquinones exhibit a unique anticancer activity. Since their discovery, medicinal
chemists have made several structural modifications, resulting in the design and synthesis of …
chemists have made several structural modifications, resulting in the design and synthesis of …
Advances in the discovery of anthraquinone-based anticancer agents
AS Tikhomirov, AA Shtil… - Recent patents on anti …, 2018 - ingentaconnect.com
Background: The anthracene-9, 10-dione (anthraquinone) derivatives represent an
exceptionally valuable class in anticancer drug development. An outstanding antitumor …
exceptionally valuable class in anticancer drug development. An outstanding antitumor …
Anthraquinone: a promising scaffold for the discovery and development of therapeutic agents in cancer therapy
Cancer, characterized by uncontrolled malignant neoplasm, is a leading cause of death in
both advanced and emerging countries. Although, ample drugs are accessible in the market …
both advanced and emerging countries. Although, ample drugs are accessible in the market …
Navigating the synthesis of quinoline hybrid molecules as promising anticancer agents
P Panda, S Chakroborty - ChemistrySelect, 2020 - Wiley Online Library
The emergence of drug resistance and low specificity with side effects are the significant
challenges in pharmaceutical sectors for control of cancer nowadays. Notwithstanding, this …
challenges in pharmaceutical sectors for control of cancer nowadays. Notwithstanding, this …
Quinoline as a privileged scaffold in cancer drug discovery
VR Solomon, H Lee - Current medicinal chemistry, 2011 - ingentaconnect.com
Quinoline (1-azanaphthalene) is a heterocyclic aromatic nitrogen compound characterized
by a double-ring structure that contains a benzene ring fused to pyridine at two adjacent …
by a double-ring structure that contains a benzene ring fused to pyridine at two adjacent …
Anthraquinones as pharmacological tools and drugs
EM Malik, CE Müller - Medicinal research reviews, 2016 - Wiley Online Library
Abstract Anthraquinones (9, 10‐dioxoanthracenes) constitute an important class of natural
and synthetic compounds with a wide range of applications. Besides their utilization as …
and synthetic compounds with a wide range of applications. Besides their utilization as …
Anthracycline and anthraquinone anticancer agents: current status and recent developments
JW Lown - Pharmacology & therapeutics, 1993 - Elsevier
The clinical treatment of neoplastic diseases relies on the complementary procedures of
surgery, radiation treatment, immunotherapy and chemotherapy. The latter technique has …
surgery, radiation treatment, immunotherapy and chemotherapy. The latter technique has …
Quinolines, a perpetual, multipurpose scaffold in medicinal chemistry
Quinoline is a versatile pharmacophore, a privileged scaffold and an outstanding fused
heterocyclic compound with a wide range of pharmacological prospective such as …
heterocyclic compound with a wide range of pharmacological prospective such as …
Antitumour anthracyclines: progress and perspectives
MB Martins‐Teixeira, I Carvalho - ChemMedChem, 2020 - Wiley Online Library
Anthracyclines are ranked among the most effective chemotherapeutics against cancer.
They are glycoside drugs comprising the amino sugar daunosamine linked to a hydroxy …
They are glycoside drugs comprising the amino sugar daunosamine linked to a hydroxy …