The regulatory role of non-coding RNAs on programmed cell death four in inflammation and cancer

M Zhao, N Zhu, F Hao, Y Song, Z Wang, Y Ni… - Frontiers in …, 2019 - frontiersin.org
Programmed cell death 4 (PDCD4) is a tumor suppressor gene implicated in many cellular
functions, including transcription, translation, apoptosis, and the modulation of different …

Interplay between non-coding RNAs and programmed cell death proteins

S Ghafouri-Fard, BM Hussen, M Mohaqiq… - Frontiers in …, 2022 - frontiersin.org
Programmed cell death (PDCD) family of proteins includes at least 12 members, function of
seven of them being more investigated. These members are PDCD1, PDCD2, PDCD4 …

miR-181b functions as an oncomiR in colorectal cancer by targeting PDCD4

Y Liu, Y Guo, H Liang, R Cheng, F Yang, Y Hong… - Protein & …, 2016 - academic.oup.com
Abstract Programmed cell death 4 (PDCD4) is a RNA-binding protein that acts as a tumor
suppressor in many cancer types, including colorectal cancer (CRC). During CRC …

Programmed cell death‐10 enhances proliferation and protects malignant T cells from apoptosis

B Lauenborg, K Kopp, T Krejsgaard, KW Eriksen… - Apmis, 2010 - Wiley Online Library
Lauenborg B, Kopp K, Krejsgaard T, Eriksen KW, Geisler C, Dabelsteen S, Gniadecki R,
Zhang Q, Wasik MA, Woetmann A, Odum N. Programmed cell death‐10 enhances …

MicroRNA‐182 promotes cell growth, invasion, and chemoresistance by targeting programmed cell death 4 (PDCD4) in human ovarian carcinomas

YQ Wang, RD Guo, RM Guo… - Journal of cellular …, 2013 - Wiley Online Library
As an important tumor suppressor, programmed cell death 4 (PDCD4) influences
transcription and translation of multiple genes, and modulates different signal transduction …

miR-93 functions as an oncomiR for the downregulation of PDCD4 in gastric carcinoma

H Liang, F Wang, D Chu, W Zhang, Z Liao, Z Fu… - Scientific reports, 2016 - nature.com
Abstract Programmed cell death 4 (PDCD4), as a tumor suppressor gene, is frequently
reduced in a variety of tumors, including gastric cancer. Previous findings have indicated …

[HTML][HTML] miR-208a-3p suppresses cell apoptosis by targeting PDCD4 in gastric cancer

K Yin, M Liu, M Zhang, F Wang, M Fen, Z Liu, Y Yuan… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Abstract Programmed cell death 4 (PDCD4) is a novel tumor suppressor gene and a
promising target for anticancer therapies. PDCD4 is frequently downregulated in various …

[HTML][HTML] Have tumor suppressor PDCD4 and its counteragent oncogenic miR-21 gone rogue?

MR Young, AN Santhanam, N Yoshikawa… - Molecular …, 2010 - ncbi.nlm.nih.gov
A recent article suggests that the well known tumor suppressor PDCD4 also functions as a
pro-inflammatory agent. The PDCD4 counteragent miR-21, a pro-oncogenic micro-RNA, is …

Role of programmed cell death 4 in diseases: A double-edged sword

Y Jiang, Y Jia, L Zhang - Cellular & Molecular Immunology, 2017 - nature.com
The molecule of programmed cell death 4 (PDCD4) is named based on its upregulation
during apoptosis. It is now known that PDCD4 is highly conserved during evolution and …

Tumor suppressor PDCD4 modulates miR-184-mediated direct suppression of C-MYC and BCL2 blocking cell growth and survival in nasopharyngeal carcinoma

Y Zhen, Z Liu, H Yang, X Yu, Q Wu, S Hua, X Long… - Cell death & …, 2013 - nature.com
Abstract Programmed cell death 4 (PDCD4), a novel tumor suppressor, inhibits cell
proliferation, migration and invasion as well as promotes cell apoptosis in tumors. However …