Liberal or Restrictive Transfusion Strategy in Patients with Traumatic Brain Injury

AF Turgeon, DA Fergusson, L Clayton… - … England Journal of …, 2024 - Mass Medical Soc
Background The effect of a liberal transfusion strategy as compared with a restrictive
strategy on outcomes in critically ill patients with traumatic brain injury is unclear. Methods …

Transfusions and long-term functional outcomes in traumatic brain injury

MA Warner, T O'Keeffe, P Bhavsar, R Shringer… - Journal of …, 2010 - thejns.org
Object In this paper, the authors' goal was to examine the relationship between transfusion
and long-term functional outcomes in moderately anemic patients (lowest hematocrit [HCT] …

[HTML][HTML] Red blood cell transfusion in patients with traumatic brain injury: a systematic review protocol

A Boutin, M Chassé, M Shemilt, F Lauzier, L Moore… - Systematic reviews, 2014 - Springer
Background Anemia is a prevalent condition in critically ill patients and red blood cell
transfusions are frequent. Although transfusions at low hemoglobin levels have been shown …

Association between relative anemia and early functional recovery after severe traumatic brain injury (TBI)

KR Carr, M Rodriguez, A Ottesen, J Michalek, C Son… - Neurocritical care, 2016 - Springer
Background Severe traumatic brain injury is associated with a multi-systemic response and
changes in metabolic demand. Patients requiring intracranial pressure monitoring or …

The effects of anaemia and transfusion on patients with traumatic brain injury: a review

S Travers, S Martin, NS Litofsky - Brain Injury, 2016 - Taylor & Francis
Background: Anaemia in traumatic brain injury (TBI) is frequently encountered.
Neurosurgical texts continue to recommend transfusion for hematocrit below 30%, despite …

Aggressive red blood cell transfusion: no association with improved outcomes for victims of isolated traumatic brain injury

ME George, DE Skarda, CR Watts, HD Pham… - Neurocritical care, 2008 - Springer
Background Clinical studies have caused blood transfusion practices in critically ill patients
to become more conservative in the last decade. However, few studies have focused on …

Safety and cost efficiency of a restrictive transfusion protocol in patients with traumatic brain injury

LB Ngwenya, CG Suen, PE Tarapore, GT Manley… - Journal of …, 2017 - thejns.org
OBJECTIVE Blood loss and moderate anemia are common in patients with traumatic brain
injury (TBI). However, despite evidence of the ill effects and expense of the transfusion of …

Retrospective evaluation of anemia and transfusion in traumatic brain injury

AP Carlson, CR Schermer, SW Lu - Journal of Trauma and Acute …, 2006 - journals.lww.com
Background: Despite clear evidence in critical care that blood transfusion has an adverse
impact on outcome, neurosurgical textbooks still recommend transfusion of patients with …

Effect of a liberal versus restrictive transfusion strategy on mortality in patients with moderate to severe head injury

LA McIntyre, DA Fergusson, JS Hutchison… - Neurocritical care, 2006 - Springer
Objective To compare a restrictive versus a liberal transfusion strategy in patients with
moderate to severe closed head injury following multiple trauma in 13 Canadian intensive …

Role of anemia in traumatic brain injury

A Salim, P Hadjizacharia, J DuBose, C Brown… - Journal of the American …, 2008 - Elsevier
BACKGROUND: Few studies have investigated the effects of anemia in patients with
traumatic brain injury (TBI). The objective of this study was to examine the role of anemia …