Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder. Oxidative
damage has been associated with pathological neuronal loss in HD. The therapeutic …

Huntington's disease (HD) is a polyglutamine-expansion disease associated to
degeneration of striatal and cortical neurons. Previously, we showed that oxidative stress …

A mutation in the huntingtin (Htt) gene produces mutant Htt and Huntington's disease (HD), a
neurodegenerative disorder. HD patients have oxidative damage in the brain, but the …

There is substantial evidence for both metabolic dysfunction and oxidative damage in
Huntington's disease (HD). In the present study, we used in vivo microdialysis to measure …

Huntington's disease (HD) is an autosomal dominant inherited neurodegenerative disorder
characterized by progressive motor dysfunction, emotional disturbances, dementia, and …

Huntington's disease (HD) is a CAG repeat disorder affecting the HD gene, which encodes
for huntingtin (Htt) and is characterized by prominent cell death in the striatum. Oxidative …

Huntington's disease (HD) is the most common polyglutamine neurodegenerative disorder
in humans, and is caused by a mutation of an unstable expansion of CAG repeats within the …

Huntington's disease (HD) is a progressive neurodegenerative disease characterized by a
severe neuronal loss that occurs primarily in the neostriatum. It has been postulated that …

Huntington's disease (HD) is a chronic neurodegenerative condition involving impaired
mitochondrial functions. The present study evaluates the therapeutic potential of combined …

Huntington's disease (HD) is a devastating neurodegenerative disorder characterized by the
progressive development of involuntary choreiform movements, cognitive impairment …