The potential to control the rate of replacement of a biodegradable implant by a tissue would
be advantageous. Here, we demonstrate that tissue invasion can be tuned through the novel …

Matrix remodeling is crucial for neovascularization, however its utilization to control this
process in synthetic biomaterials has been limited. Here, we utilized hyaluronic acid (HA) …

Biomaterials with attenuated adverse host tissue reactions, and meanwhile, combining
biocompatibility with mimicry of mechanical and biochemical cues of native extracellular …

In recent years, therapeutic angiogenesis has been sought as a treatment for many vascular
disorders, including peripheral artery disease and coronary artery disease. As mechanisms …

The volume of tissue that can be engineered is limited by the extent to which vascularization
can be stimulated within the scaffold. The ability of a scaffold to induce vascularization is …

Successful tissue regeneration requires that biomaterials have optimal bioactivity and
mechanical properties. Heparin-containing hydrogels that can be crosslinked in situ were …

Materials that support the assembly of new vasculature are critical for regenerative
medicine. Controlling the scaffold's mechanical properties may help to optimize …

Regulation of the rate of cell ingrowth into and within a matrix is desirable for efficient tissue
regeneration. Polyethylene glycol hydrogels crosslinked with matrix metalloproteinase …

To achieve the task of fabricating functional tissues, scaffold materials that can be sufficiently
vascularized to mimic functionality and complexity of native tissues are yet to be developed …

Slow vascularization of functional blood limits the transplantation of tissue constructs and the
recovery of ischemic and wounded tissues. Despite the widespread investigation of …