Roles of cancer/testis antigens (CTAs) in breast cancer
Y Li, J Li, Y Wang, Y Zhang, J Chu, C Sun, Z Fu… - Cancer letters, 2017 - Elsevier
Breast cancer is the most common cancer diagnosed and is the second leading cause of
cancer death among women in the US. For breast cancer, early diagnosis and efficient …
cancer death among women in the US. For breast cancer, early diagnosis and efficient …
Cancer testis antigens as immunogenic and oncogenic targets in breast cancer
AM Mahmoud - Immunotherapy, 2018 - Taylor & Francis
Breast cancer cells frequently express tumor-associated antigens that can elicit immune
responses to eradicate cancer. Cancer-testis antigens (CTAs) are a group of tumor …
responses to eradicate cancer. Cancer-testis antigens (CTAs) are a group of tumor …
Cancer-testis antigens in triple-negative breast cancer: role and potential utility in clinical practice
RA Lam, TZ Tien, CR Joseph, JX Lim, AA Thike, J Iqbal… - Cancers, 2021 - mdpi.com
Simple Summary Triple-negative breast cancer (TNBC) has been associated with worse
prognoses due to the limited treatment options. Thus, there is a need to characterise new …
prognoses due to the limited treatment options. Thus, there is a need to characterise new …
Comprehensive functional characterization of cancer–testis antigens defines obligate participation in multiple hallmarks of cancer
KE Maxfield, PJ Taus, K Corcoran, J Wooten… - Nature …, 2015 - nature.com
Tumours frequently activate genes whose expression is otherwise biased to the testis,
collectively known as cancer–testis antigens (CTAs). The extent to which CTA expression …
collectively known as cancer–testis antigens (CTAs). The extent to which CTA expression …
Cancer testes antigens in breast cancer: biological role, regulation, and therapeutic applicability
A Pandey, A Kurup, A Shrivastava, S Radhi… - International Reviews …, 2012 - Taylor & Francis
Breast cancer remains one of the leading causes of death among women across the world.
The last few decades have seen significant reduction in mortality owing to earlier detection …
The last few decades have seen significant reduction in mortality owing to earlier detection …
Cancer testis antigens and NY-BR-1 expression in primary breast cancer: prognostic and therapeutic implications
D Balafoutas, A Zur Hausen, S Mayer, M Hirschfeld… - BMC cancer, 2013 - Springer
Background Cancer–testis antigens (CTA) comprise a family of proteins, which are
physiologically expressed in adult human tissues solely in testicular germ cells and …
physiologically expressed in adult human tissues solely in testicular germ cells and …
Cancer–testis genes as candidates for immunotherapy in breast cancer
Cancer–testis (CT) antigens are tumor-associated antigens attracting immunologists for their
possible application in the immunotherapy of cancer. Several clinical trials have assessed …
possible application in the immunotherapy of cancer. Several clinical trials have assessed …
[HTML][HTML] Cancer–testis antigen expression in triple-negative breast cancer
G Curigliano, G Viale, M Ghioni, AA Jungbluth… - Annals of oncology, 2011 - Elsevier
Abstract Background: Cancer–testis (CT) antigens, frequently expressed in human germline
cells but not in somatic tissues, may become aberrantly reexpressed in different cancer …
cells but not in somatic tissues, may become aberrantly reexpressed in different cancer …
Cancer/testis antigens: expression, regulation, tumor invasion, and use in immunotherapy of cancers
A Salmaninejad, MR Zamani… - Immunological …, 2016 - Taylor & Francis
Cancer/testis antigens (CTAs) are named based on their expression pattern that is restricted
in a number of normal and abnormal tissues. Tumor cells frequently express antigens whose …
in a number of normal and abnormal tissues. Tumor cells frequently express antigens whose …
Expression of four cancer-testis antigens in TNBC indicating potential universal immunotherapeutic targets
J Xiao, F Huang, L Li, L Zhang, L Xie, B Liu - Journal of Cancer Research …, 2023 - Springer
Objective Immunotherapy is an attractive treatment for breast cancer. Cancer-testis antigens
(CTAs) are potential targets for immunotherapy for their restricted expression. Here, we …
(CTAs) are potential targets for immunotherapy for their restricted expression. Here, we …