Apoptotic cell death is usually a response to the cell's microenvironment. In the kidney,
apoptosis contributes to parenchymal cell loss in the course of acute and chronic renal …

Disorders of cell number that result from an imbalance between the death of parenchymal
cells and the proliferation or recruitment of maladaptive cells contributes to the pathogenesis …

Acute tubular necrosis causes a loss of renal function, which clinically presents as acute
kidney failure (AKI). The biochemical signaling pathways that trigger necrosis have been …

Acute renal failure (ARF) can be defined as a sudden loss of renal function and is a common
and serious clinical problem. There are many causes of ARF but the most common cause …

Death of renal cells is central to the pathophysiology of acute tubular necrosis,
autoimmunity, necrotizing glomerulonephritis, cystic kidney disease, urosepsis, delayed …

In humans and experimental models of renal ischemia, tubular cells in various nephron
segments undergo necrotic and/or apoptotic cell death. Various factors, including nucleotide …

Understanding nephron loss is a primary strategy for preventing CKD progression. Death of
renal tubular cells may occur by apoptosis during developmental and regenerative …

Ischemia-reperfusion injury (IRI) is the outcome of an inflammatory process that is triggered
when an organ undergoes a transient reduction or cessation of blood flow, followed by re …

Apoptotic cell death is usually a response to the cell microenvironment. Apoptosis requires
the activation of lethal molecules and the inactivation of prosurvival ones. Both are potential …

Apoptotic pathways in ischemic acute renal failure. The study of cell death has emerged as
an important and exciting area of research in cell biology. Although two kinds of cell death …