Background Hyperuricemia is associated with reduced survival among patients with heart
failure (HF), but the effect of gout on HF outcomes is unknown. A recent randomized trial …

Background The prevalence of hyperuricemia, gout, and heart failure (HF) is on the rise, and
these conditions often share similar risk factors. The present study aimed to evaluate the …

BACKGROUND: Hyperuricemia is associated with worse outcomes of patients with chronic
heart failure (HF). However, it is unknown in an unselected HF patients encountered in …

BACKGROUND: Previous studies have not extensively examined the association of
hyperuricemia and adverse outcomes in systolic heart failure (HF) in relation to xanthine …

STUDY OBJECTIVE: The aim of this study was to explore the prognostic role of serum uric
acid (UA) measurement in the hospital and long-term mortality assessment in subjects with …

Background: Two recent randomized clinical trials of escalating doses of allopurinol for the
progression of chronic kidney disease (CKD) reported no benefits but potentially increased …

OBJECTIVE: Uric acid (UA) levels are frequently increased in patients with heart failure (HF),
and may be an indicator of a poor prognosis and an innovative target for treatment. We …

Objective: To examine whether allopurinol is associated with any alteration in mortality and
hospitalisations in patients with chronic heart failure (CHF). This hypothesis is based on …

Background An association between uric acid (UA) and cardiovascular diseases, including
heart failure (HF), has been reported. However, whether UA is a causal risk factor for HF is …

Background Hyperuricemia and gout have been associated with increased cardiovascular
risk. Allopurinol is an effective urate-lowering drug. Whether lowering of urate by allopurinol …