Antibodies against native and oxidized cardiolipin and phosphatidylserine and phosphorylcholine in atherosclerosis development
AG Frostegård, J Su, X Hua, M Vikström, U de Faire… - PLoS …, 2014 - journals.plos.org
Background Antibodies against cardiolipin and phosphatidylserine (anti-CL and anti-PS) are
associated with thrombosis. In contrast, we determined that IgM antibodies against oxidized …
associated with thrombosis. In contrast, we determined that IgM antibodies against oxidized …
Antibodies of IgM subclass to phosphorylcholine and oxidized LDL are protective factors for atherosclerosis in patients with hypertension
J Su, A Georgiades, R Wu, T Thulin, U de Faire… - Atherosclerosis, 2006 - Elsevier
OBJECTIVE: To determine the importance of antibodies against phosphorylcholine (PC) and
oxidized low density lipoprotein (OxLDL) for development of atherosclerosis. METHODS …
oxidized low density lipoprotein (OxLDL) for development of atherosclerosis. METHODS …
[HTML][HTML] IgM phosphorylcholine antibodies inhibit cell death and constitute a strong protection marker for atherosclerosis development, particularly in combination with …
R Fiskesund, J Su, I Bulatovic, M Vikström… - Results in …, 2012 - Elsevier
Background We have reported that anti-phosphorylcholine (anti-PC) IgM is a protection
marker for human cardiovascular disease (CVD) and atherosclerosis. We here investigate …
marker for human cardiovascular disease (CVD) and atherosclerosis. We here investigate …
Low levels of antibodies against oxidized but not nonoxidized cardiolipin and phosphatidylserine are associated with atherosclerotic plaques in systemic lupus …
J Su, AG Frostegård, X Hua, T Gustafsson… - The Journal of …, 2013 - jrheum.org
Objective. We have reported that the prevalence of atherosclerotic plaques and their
echolucency was increased in systemic lupus erythematosus (SLE). We here study …
echolucency was increased in systemic lupus erythematosus (SLE). We here study …
Low levels of IgM antibodies to oxidized cardiolipin increase and high levels decrease risk of cardiovascular disease among 60-year olds: a prospective study
J Su, X Hua, M Vikström, K Leander, B Gigante… - BMC Cardiovascular …, 2013 - Springer
Background Antibodies against cardiolipin (aCL) are associated with increased risk of
cardiovascular disease (CVD). We here determine the role of antibodies against oxidized …
cardiovascular disease (CVD). We here determine the role of antibodies against oxidized …
IgM antibodies to oxidized phosphatidylserine as protection markers in cardiovascular disease among 60-year olds
J Frostegård, J Su, S Sing, X Hua, M Vikström… - Plos one, 2017 - journals.plos.org
Objective Phosphatidylserine is exposed on apoptotic cells and is prone to oxidation
(OxPS). Here we analyze the association of IgM antibodies against OxPS (anti-OxPS) with …
(OxPS). Here we analyze the association of IgM antibodies against OxPS (anti-OxPS) with …
Autoantibodies in atherosclerosis
J FROSTEGARD - Autoantibodies, 2007 - Elsevier
Atherosclerosis is an inflammatory disease of middle and large arteries, where activated,
cytokine-producing T cells and monocytes are already present at an early stage of disease …
cytokine-producing T cells and monocytes are already present at an early stage of disease …
Anticardiolipin Antibodies From Patients With the Antiphospholipid Antibody Syndrome Recognize Epitopes in Both β2-Glycoprotein 1 and Oxidized Low-Density …
S Hörkkö, T Olee, L Mo, DW Branch, VL Woods Jr… - Circulation, 2001 - Am Heart Assoc
Background—We recently suggested that many anticardiolipin antibodies bind only to
oxidized cardiolipin (OxCL) and/or to OxCL–β2-glycoprotein 1 (β2GP1) adducts but not to a …
oxidized cardiolipin (OxCL) and/or to OxCL–β2-glycoprotein 1 (β2GP1) adducts but not to a …
Anti-cardiolipin antibodies and risk of myocardial infarction in a prospective cohort of middle-aged men
O Vaarala, M Mänttäri, V Manninen, L Tenkanen… - Circulation, 1995 - Am Heart Assoc
Background Data concerning the relation between anti-phospholipid (aPL) antibodies and
myocardial infarction in subjects without evidence of overt autoimmune disease are …
myocardial infarction in subjects without evidence of overt autoimmune disease are …
Low level natural antibodies against phosphorylcholine: a novel risk marker and potential mechanism in atherosclerosis and cardiovascular disease
J Frostegård - Clinical immunology, 2010 - Elsevier
Atherosclerosis is an inflammatory condition characterised by an abundance of activated
immunocompetent cells in plaques which cause cardiovascular disease (CVD) when they …
immunocompetent cells in plaques which cause cardiovascular disease (CVD) when they …
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