Acute pancreatitis (AP) is serious inflammatory disease of the pancreas. Accumulating
evidence links diabetes with severity of AP, suggesting that endogenous insulin may be …

Acute pancreatitis is a serious and sometimes fatal inflammatory disease where the
pancreas digests itself. The non-oxidative ethanol metabolites palmitoleic acid (POA) and …

Acute pancreatitis is a serious and sometimes fatal inflammatory disease of the pancreas
without any reliable treatment or imminent cure. In recent years, impaired metabolism and …

Pancreatitis is an increasingly common and sometimes severe disease that lacks a specific
therapy. The pathogenesis of pancreatitis is still not well understood. Calcium (Ca 2+) is a …

Acute pancreatitis (AP) is a potentially lethal inflammatory disease that lacks specific
therapy. Damaged pancreatic acinar cells are believed to be the site of AP initiation. The …

Proper mitochondrial function and adequate cellular ATP are necessary for normal
pancreatic protein synthesis and sorting, maintenance of intracellular organelles and …

Aberrant cytosolic Ca2+ flux in pancreatic acinar cells is critical to the pathological
pancreatic zymogen activation observed in acute pancreatitis, but the downstream effectors …

Acute pancreatitis is an increasingly common and sometimes severe disease for which there
is little specific therapy. Chronic pancreatitis is a common and grossly debilitating sequel …

The incidence of acute pancreatitis continues to increase worldwide, and it is one of the
most common gastrointestinal causes for hospital admission in the USA. In the past decade …

Recent advances challenge the long-believed trypsin-centered understanding of
pancreatitis. It is becoming increasingly clear that activation of intense inflammatory …