Dendritic cells (DCs) develop in the bone marrow from haematopoietic progenitors that have
numerous shared characteristics between mice and humans. Human counterparts of mouse …

The dendritic cells (DCs) of the immune system function in innate and adaptive responses
by directing activity of various effector cells rather than serving as effectors themselves. DCs …

Although much progress has been made in the understanding of the ontogeny and function
of dendritic cells (DCs), the transcriptional regulation of the lineage commitment and …

Dendritic cells (DCs) are major regulators of adaptive immunity, as they are not only capable
to induce efficient immune responses, but are also crucial to maintain peripheral tolerance …

Functional specialization allows defined dendritic-cell (DC) subsets to induce efficient
defence mechanisms against pathogens and tumour cells, and maintain T-cell tolerance by …

Two distinct dendritic cell (DC) subsets, conventional DCs (cDCs) and plasmacytoid DCs
(pDCs), have been shown to develop via either the myeloid or the lymphoid pathway in …

The developmental pathways that lead to the production of antigen-presenting dendritic
cells (DCs) are beginning to be understood. These are the last of the pathways of …

Dendritic cells (DCs) form a remarkable cellular network that shapes adaptive immune
responses according to peripheral cues. After four decades of research, we now know that …

The study of murine dendritic cell (DC) development has been integral to the identification of
specialized DC subsets that have unique requirements for their form and function. Advances …

Dendritic cells (DCs) are a heterogeneous group of functionally specialized antigen-
presenting cells that initiate and orchestrate immune responses. Our understanding of DC …