Construction and phenotypic characterization of HIV type 1 functional envelope clones of subtypes G and F
A Revilla, E Delgado, EC Christian… - AIDS research and …, 2011 - liebertpub.com
Subtype G has been estimated to represent the fourth most prevalent clade in the HIV-1
pandemic and subtype F is widely circulating in parts of South America (frequently within BF …
pandemic and subtype F is widely circulating in parts of South America (frequently within BF …
HIV-1 subtype A envelope variants from early in infection have variable sensitivity to neutralization and to inhibitors of viral entry
CA Blish, R Nedellec, K Mandaliya, DE Mosier… - Aids, 2007 - journals.lww.com
Background: An effective HIV-1 vaccine or microbicide must block the transmitted virus
variants that initially establish a new infection; consequently, it is critical that such viruses be …
variants that initially establish a new infection; consequently, it is critical that such viruses be …
Cryptic nature of a conserved, CD4-inducible V3 loop neutralization epitope in the native envelope glycoprotein oligomer of CCR5-restricted, but not CXCR4-using …
The external subunit of the human immunodeficiency virus type 1 (HIV-1) envelope
glycoprotein (Env), gp120, contains conserved regions that mediate sequential interactions …
glycoprotein (Env), gp120, contains conserved regions that mediate sequential interactions …
Increased neutralization sensitivity of recently emerged CXCR4-using human immunodeficiency virus type 1 strains compared to coexisting CCR5-using variants from …
EM Bunnik, ED Quakkelaar, AC Van Nuenen… - Journal of …, 2007 - Am Soc Microbiol
ABSTRACT CXCR4-using (X4) human immunodeficiency virus type 1 (HIV-1) variants
evolve from CCR5-using (R5) variants relatively late in the natural course of infection in 50 …
evolve from CCR5-using (R5) variants relatively late in the natural course of infection in 50 …
Coreceptor tropism in human immunodeficiency virus type 1 subtype D: high prevalence of CXCR4 tropism and heterogeneous composition of viral populations
W Huang, SH Eshleman, J Toma, S Fransen… - Journal of …, 2007 - Am Soc Microbiol
In human immunodeficiency virus type 1 (HIV-1) subtype B, CXCR4 coreceptor use ranges
from∼ 20% in early infection to∼ 50% in advanced disease. Coreceptor use by non …
from∼ 20% in early infection to∼ 50% in advanced disease. Coreceptor use by non …
Genetic and Phenotypic Analysis of CRF01_AE HIV-1 env Clones from Patients Residing in Beijing, China
D Chen, X He, J Ye, P Zhao, Y Zeng… - AIDS research and …, 2016 - liebertpub.com
CRF01_AE is one of the four dominant HIV-1 strains circulating in China. In this study, we
performed genetic and phenotypic analyses using a total of 60 full-length envelope gene …
performed genetic and phenotypic analyses using a total of 60 full-length envelope gene …
[HTML][HTML] The neutralization sensitivity of viruses representing human immunodeficiency virus type 1 variants of diverse subtypes from early in infection is dependent on …
Neutralization properties of human immunodeficiency virus (HIV-1) are often defined using
pseudoviruses grown in transformed cells, which are not biologically relevant HIV-1 …
pseudoviruses grown in transformed cells, which are not biologically relevant HIV-1 …
Generation and structural analysis of soluble oligomeric gp140 envelope proteins derived from neutralization-resistant and neutralization-susceptible primary HIV type …
L Stamatatos, M Lim, C Cheng-Mayer - AIDS research and human …, 2000 - liebertpub.com
We generated DNA constructs expressing soluble truncated forms of the envelope of SF162,
a neutralizationresistant primary human immunodeficiency virus type 1 isolate, and SF162 …
a neutralizationresistant primary human immunodeficiency virus type 1 isolate, and SF162 …
V3 loop truncations in HIV-1 envelope impart resistance to coreceptor inhibitors and enhanced sensitivity to neutralizing antibodies
MM Laakso, FH Lee, B Haggarty, C Agrawal… - PLoS …, 2007 - journals.plos.org
The V1/V2 region and the V3 loop of the human immunodeficiency virus type I (HIV-1)
envelope (Env) protein are targets for neutralizing antibodies and also play an important …
envelope (Env) protein are targets for neutralizing antibodies and also play an important …
Genotypic characterization and comparison of full-length envelope glycoproteins from South African HIV type 1 subtype C primary isolates that utilize CCR5 and/or …
K Michler, BJ Connell, WDF Venter… - AIDS research and …, 2008 - liebertpub.com
CCR5 has preferentially been used by all circulating HIV-1 subtype C viruses for cell entry.
Recently, we reported the highest proportion of CXCR4-utilizing primary isolates among a …
Recently, we reported the highest proportion of CXCR4-utilizing primary isolates among a …