[HTML][HTML] Cellular and functional heterogeneity of the airway epithelium

JD Davis, TP Wypych - Mucosal immunology, 2021 - Elsevier
The airway epithelium protects us from environmental insults, which we encounter with
every breath. Not only does it passively filter large particles, it also senses potential danger …

Regulation of immune responses by the airway epithelial cell landscape

RJ Hewitt, CM Lloyd - Nature Reviews Immunology, 2021 - nature.com
The community of cells lining our airways plays a collaborative role in the preservation of
immune homeostasis in the lung and provides protection from the pathogens and pollutants …

Innate immune functions of the airway epithelium

JA Bartlett, AJ Fischer, B Paul Jr - Trends in Innate Immunity, 2008 - karger.com
The epithelium of the respiratory tract forms a large surface area that maintains intimate
contact with the environment. Through the act of breathing, this mucosal surface encounters …

The airway epithelium: more than just a structural barrier

A Tam, S Wadsworth, D Dorscheid… - Therapeutic …, 2011 - journals.sagepub.com
The mammalian airway is lined by a variety of specialized epithelial cells that not only serve
as a physical barrier but also respond to environment-induced damage through the release …

The innate immune function of airway epithelial cells in inflammatory lung disease

PS Hiemstra, PB McCray, R Bals - European respiratory …, 2015 - Eur Respiratory Soc
The airway epithelium is now considered to be central to the orchestration of pulmonary
inflammatory and immune responses, and is also key to tissue remodelling. It acts as the first …

Epithelial barriers in allergy and asthma

PW Hellings, B Steelant - Journal of Allergy and Clinical Immunology, 2020 - Elsevier
The respiratory epithelium provides a physical, functional, and immunologic barrier to
protect the host from the potential harming effects of inhaled environmental particles and to …

Epithelial cells and airway diseases

D Proud, R Leigh - Immunological reviews, 2011 - Wiley Online Library
The airway epithelial cell is the initial cell type impacted both by inhaled environmental
factors, such as pathogens, allergens, and pollutants, and inhaled medications for airway …

Airway basal cells, protectors of epithelial walls in health and respiratory diseases

E Ruysseveldt, K Martens, B Steelant - Frontiers in Allergy, 2021 - frontiersin.org
The airway epithelium provides a critical barrier to the outside environment. When its
integrity is impaired, epithelial cells and residing immune cells collaborate to exclude …

[HTML][HTML] Innate immune responses of the airway epithelium

JH Ryu, CH Kim, JH Yoon - Molecules and cells, 2010 - Elsevier
Barrier epithelia, especially airway epithelial cells, are persistently exposed to micro-
organisms and environmental factors. To protect the host from these microbial challenges …

The airway epithelium is central to the pathogenesis of asthma

ST Holgate - Allergology International, 2008 - jstage.jst.go.jp
Asthma is an inflammatory disorder principally involving the conducting airways and
characterised by infiltration of the airway wall with a range of inflammatory cells driven in …