[HTML][HTML] Afriplex GRTTM extract attenuates hepatic steatosis in an in vitro model of NAFLD
K Gabuza, TI Mabuda, O Patel, N Khuboni… - Plos one, 2024 - journals.plos.org
Background Currently, it is acknowledged that vitamin E, insulin sensitizers and anti-diabetic
drugs are used to manage non-alcoholic fatty liver disease (NAFLD), however, these …
drugs are used to manage non-alcoholic fatty liver disease (NAFLD), however, these …
[HTML][HTML] Celastrol ameliorates liver metabolic damage caused by a high-fat diet through Sirt1
Y Zhang, C Geng, X Liu, M Li, M Gao, X Liu, F Fang… - Molecular …, 2017 - Elsevier
Objective Celastrol was recently identified as a potential novel treatment for obesity.
However, the effect of Celastrol on nonalcoholic fatty liver disease (NAFLD) remains elusive …
However, the effect of Celastrol on nonalcoholic fatty liver disease (NAFLD) remains elusive …
2, 3, 5, 4′-tetrahydroxy-stilbene-2-O-β-D-glucoside ameliorates NAFLD via attenuating hepatic steatosis through inhibiting mitochondrial dysfunction dependent on …
S Zhang, Z Wu, L Shi, S Yan, Z Huang, B Lu, Z Wang… - Phytomedicine, 2022 - Elsevier
Background Non-alcoholic fatty liver disease (NAFLD) is becoming more and more common
in clinic in the world, and the study on its mechanism and treatment strategy has already …
in clinic in the world, and the study on its mechanism and treatment strategy has already …
[HTML][HTML] A new NRF2 activator for the treatment of human metabolic dysfunction-associated fatty liver disease
A Hammoutene, S Laouirem, M Albuquerque, N Colnot… - JHEP Reports, 2023 - Elsevier
Background & Aims Oxidative stress triggers metabolic-associated fatty liver disease
(MAFLD) and fibrosis. Previous animal studies demonstrated that the transcription factor …
(MAFLD) and fibrosis. Previous animal studies demonstrated that the transcription factor …
Targeting antioxidant factor Nrf2 by raffinose ameliorates lipid dysmetabolism-induced pyroptosis, inflammation and fibrosis in NAFLD
J Liu, Y Zheng, S Yang, L Zhang, B Liu, J Zhang, X Yu… - Phytomedicine, 2024 - Elsevier
Background Non-alcoholic fatty liver disease (NAFLD) is a persistent liver condition that
affects both human health and animal productive efficiency on a global scale. A number of …
affects both human health and animal productive efficiency on a global scale. A number of …
Pterostilbene alleviated NAFLD via AMPK/mTOR signaling pathways and autophagy by promoting Nrf2
B Shen, Y Wang, J Cheng, Y Peng, Q Zhang, Z Li… - Phytomedicine, 2023 - Elsevier
Background NAFLD is a liver disease that is caused by liver damage or extreme lipid
deposition but not alcohol. Nrf2 could mediate resistance to oxidative stress injury …
deposition but not alcohol. Nrf2 could mediate resistance to oxidative stress injury …
Tangeretin improves hepatic steatosis and oxidative stress through the Nrf2 pathway in high fat diet-induced nonalcoholic fatty liver disease mice
Z Ke, S Tan, H Li, S Jiang, Y Li, R Chen, M Li - Food & Function, 2022 - pubs.rsc.org
Nonalcoholic liver disease (NAFLD) is a pathological condition characterized by excessive
fat deposition in the liver, and NAFLD usually has a close relationship with obesity or …
fat deposition in the liver, and NAFLD usually has a close relationship with obesity or …
Roflumilast ameliorates GAN diet-induced non-alcoholic fatty liver disease by reducing hepatic steatosis and fibrosis in ob/ob mice
B Wang, X Zhu, S Yu, H Xue, L Deng, Y Zhang… - Biochemical and …, 2024 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is a highly prevalent progressive liver disease.
Currently, there is only one drug for NAFLD treatment, and the options are limited …
Currently, there is only one drug for NAFLD treatment, and the options are limited …
Seed oil of Rosa roxburghii Tratt against non-alcoholic fatty liver disease in vivo and in vitro through PPARα/PGC-1α-mediated mitochondrial oxidative metabolism
HY Ni, L Yu, XL Zhao, LT Wang, CJ Zhao, H Huang… - Phytomedicine, 2022 - Elsevier
Background Non-alcoholic fatty liver disease (NAFLD), characterized by hepatic steatosis
and hepatocyte injury, is an obesity-induced metabolic dysregulation with few available …
and hepatocyte injury, is an obesity-induced metabolic dysregulation with few available …
[HTML][HTML] Rosmarinic acid attenuates hepatic steatosis by modulating ER stress and autophagy in oleic acid-induced HepG2 cells
GJ Balachander, S Subramanian, K Ilango - RSC advances, 2018 - pubs.rsc.org
Non-alcoholic fatty acid disease (NAFLD) has become an emerging entity of liver disorders
worldwide. Oxidative stress and deranged autophagy-induced endoplasmic reticulum (ER) …
worldwide. Oxidative stress and deranged autophagy-induced endoplasmic reticulum (ER) …