Antiviral drug resistance: mechanisms and clinical implications

L Strasfeld, S Chou - Infectious Disease Clinics, 2010 - id.theclinics.com
In the setting of intensive immunosuppression for the management of rejection in solid organ
transplant (SOT) recipients, or graft-versus-host disease (GVHD) in hematopoietic stem cell …

" The end of innocence" revisited: resistance of herpesviruses to antiviral drugs

AK Field, KK Biron - Clinical microbiology reviews, 1994 - Am Soc Microbiol
In the past 4 years, interest in drug-resistant herpesviruses has evolved from the realm of
academic laboratory studies to that of great clinical importance. Recurrent and persistent …

Cytomegalovirus drug resistance and clinical implications

SW Chou - Transplant Infectious Disease, 2001 - Wiley Online Library
Antiviral agents are commonly used for cytomegalovirus (CMV) prophylaxis or therapy after
solid organ transplantation. Until recently, the detection of drug‐resistant CMV in this setting …

High rate of cytomegalovirus drug resistance among patients receiving preemptive antiviral treatment after haploidentical stem cell transplantation

E Shmueli, R Or, MY Shapira, IB Resnick… - The Journal of …, 2014 - academic.oup.com
We examined the rate, clinical impact, and risk factors of cytomegalovirus (CMV) drug
resistance in 561 patients who underwent 616 hematopoietic stem cell transplantations …

Resistance to antiviral drugs in herpes simplex virus infections among allogeneic stem cell transplant recipients: risk factors and prognostic significance

S Chakrabarti, D Pillay, D Ratcliffe… - Journal of Infectious …, 2000 - academic.oup.com
Herpes simplex virus (HSV) infections in 75 allogeneic stem cell transplant recipients were
analyzed. Sixteen patients developed HSV disease following transplantation. The risk …

Antiviral drug resistance in herpesviruses other than cytomegalovirus

J Piret, G Boivin - Reviews in medical virology, 2014 - Wiley Online Library
The discovery of acyclovir (ACV), a nucleoside analogue, more than 30 years ago,
represents a milestone in the management of HSV and VZV infections. The modest activity …

Human cytomegalovirus antiviral drug resistance in hematopoietic stem cell transplantation: current state of the art

AB Campos, J Ribeiro, D Boutolleau… - Reviews in medical …, 2016 - Wiley Online Library
Human cytomegalovirus (HCMV) infection is a major cause of morbidity and mortality in
allogeneic hematopoietic stem cell transplant recipients. The significant clinical impact of …

Clinical and biologic aspects of human cytomegalovirus resistance to antiviral drugs

F Baldanti, N Lurain, G Gerna - Human immunology, 2004 - Elsevier
The emergence of human cytomegalovirus (HCMV) drug resistant strains is a life-
threatening condition in immunocompromised individuals with active HCMV infection …

Definitions of resistant and refractory cytomegalovirus infection and disease in transplant recipients for use in clinical trials

RF Chemaly, S Chou, H Einsele… - Clinical Infectious …, 2019 - academic.oup.com
Despite advances in preventive strategies, cytomegalovirus (CMV) infection remains a major
complication in solid organ and hematopoietic cell transplant recipients. CMV infection may …

How I treat resistant cytomegalovirus infection in hematopoietic cell transplantation recipients

F El Chaer, DP Shah… - Blood, The Journal of the …, 2016 - ashpublications.org
Cytomegalovirus (CMV) infection is a significant complication in hematopoietic cell
transplantation (HCT) recipients. Four antiviral drugs are used for preventing or treating …