Amyloid aggregation is a hallmark of several degenerative diseases affecting the brain or
peripheral tissues, whose intermediates (oligomers, protofibrils) and final mature fibrils …

Protein and peptides are converted from their soluble forms into highly ordered fibrillar
aggregates under various conditions inside the cell. Such transitions confer diverse …

Protein misfolding and aggregation into fibrillar deposits is a common feature of a large
group of degenerative diseases affecting the central nervous system or peripheral organs …

Biomolecular self-assembly is a fundamental process in all organisms. As primary
components of the life molecular machinery, proteins have a vast array of resources …

Amyloid fibrils are a special class of self-assembled protein molecules, which exhibit various
toxic effects in cells. Different physiological disorders such as Alzheimer's, Parkinson's …

The formation of well‐ordered fibrillar protein deposits is common to a large group of
amyloid‐associated disorders. This group consists of several major human diseases such …

Protein misfolding diseases (PMDs) are chronic and progressive, with no effective therapy
so far. Aggregation and misfolding of amyloidogenic proteins are closely associated with the …

Alzheimer's disease is the most common neurodegenerative disease and is one of the main
causes of death in developed countries. Consumption of foods rich in polyphenolics is …

Protein misfolding and aggregation can be induced by a wide variety of factors, such as
dominant disease-associated mutations, changes in the environmental conditions (pH …

Amyloid fibrillation of proteins and polypeptides and their deposition in cells and tissues is
associated with a number of pathological states collectively known as amyloid disorders …