Systemic baclofen stimulates gastric motility and secretion via a central action in the rat.

PL Andrews, KL Wood - British journal of pharmacology, 1986 - ncbi.nlm.nih.gov
Abstract Intravenous (0.5 mg kg-1) or subcutaneous (2-16 mg kg-1) administration of the
gamma-aminobutyric acid (GABA) analogue baclofen resulted in a stimulation of gastric …

Effects of GABA antagonists and structural GABA analogues on baclofen stimulated gastric acid secretion in the rat

N HARA, Y HARA, Y GOTO - The Japanese Journal of …, 1990 - jstage.jst.go.jp
The effects of GABA receptor antagonists (bicuculline and phaclofen) and structural GABA-
analogues on baclofen stimulated gastric acid secretion were studied in standardized …

Gastric acid and vagus nerve response to GABA agonist baclofen

Y Goto, Y Tache, H Debas, D Novin - Life sciences, 1985 - Elsevier
Abstract Baclofen [beta-(p-chlorophenyl)-gamma-aminobutyric acid], a lipophilic derivative
of GABA, was studied for its effect upon the efferent activity of the left cervical vagus in …

The effect of the GABAB receptor agonist baclofen on liquid and solid gastric emptying in mice

E Symonds, R Butler, T Omari - European journal of pharmacology, 2003 - Elsevier
The effect of the GABAB receptor agonist baclofen, a potential treatment for
gastroesophageal reflux, on gastric emptying has not been determined. The effect of 1–4 …

Modulation of the vagal drive to the intramural cholinergic and non‐cholinergic neurones in the ferret stomach by baclofen.

PL Andrews, S Bingham, KL Wood - The Journal of Physiology, 1987 - Wiley Online Library
1. In the urethane‐anaesthetized ferret vagotomy (cervical and abdominal) and
hexamethonium both produced an increase in gastric corpus pressure after treatment with …

Food intake suppressant effect of baclofen in rats.

MR Zarrindast, T Hosseini-Nia… - General …, 1989 - europepmc.org
1. Baclofen given intraperitoneally (ip) to rats caused a dose-dependent decrease in food
intake. 2. Bicuculline or picrotoxin (GABAA-antagonist) and methergoline (5-HT antagonist) …

Body temperature-dependent action of baclofen in rat stomach: Relation to acid secretion and ulcerogenicity

K Takeuchi, H Nishiwaki, H Niida, S Okabe - Digestive diseases and …, 1990 - Springer
The effect of baclofen (PCPGABA) on acid secretion, motility, and mucosa was investigated
in the anesthetized rat stomach under various body temperatures (BT: 28–38° C), and they …

Baclofen analgesia: involvement of the GABAergic system

GN Balerio, MC Rubio - Pharmacological research, 2002 - Elsevier
The effect of baclofen, a GABAB agonist, has been studied in the hot plate test in mice, to
analyze the possible involvement of the GABAergic system in baclofen analgesia. Baclofen …

The effect of systemic administration of baclofen on food intake in rats

IS Ebenezer, AK Pringle - Neuropharmacology, 1992 - Elsevier
The effects of systemic administration of the GABA B agonist, baclofen was investigated on
food intake in non-fasted rats. Baclofen (1.0, 2.0 and 4.0 mg kg, sc) produced a dose-related …

Intraperitoneal administration of baclofen increases consumption of both solid and liquid diets in rats

IS Ebenezer - European journal of pharmacology, 1995 - Elsevier
It has previously been demonstrated that systemic administration of the GABAB receptor
agonist baclofen increases food intake but decreases water intake in rats. In the present …