Preparation and characterization of Tamoxifen citrate loaded nanoparticles for breast cancer therapy
R Maji, NS Dey, BS Satapathy… - International journal …, 2014 - Taylor & Francis
Background Four formulations of Tamoxifen citrate loaded polylactide-co-glycolide (PLGA)
based nanoparticles (TNPs) were developed and characterized. Their internalization by …
based nanoparticles (TNPs) were developed and characterized. Their internalization by …
Biodegradable poly (ε-caprolactone) nanoparticles for tumor-targeted delivery of tamoxifen
JS Chawla, MM Amiji - International journal of pharmaceutics, 2002 - Elsevier
To increase the local concentration of tamoxifen in estrogen receptor (ER) positive breast
cancer, we have developed and characterized nanoparticle formulation using poly (ε …
cancer, we have developed and characterized nanoparticle formulation using poly (ε …
Development of biodegradable polymer based tamoxifen citrate loaded nanoparticles and effect of some manufacturing process parameters on them: a …
B Sahana, K Santra, S Basu… - International journal of …, 2010 - Taylor & Francis
The aim of the present study was to develop nanoparticles of tamoxifen citrate, a non-
steroidal antiestrogenic drug used for the treatment of breast cancer. Biodegradable poly (D …
steroidal antiestrogenic drug used for the treatment of breast cancer. Biodegradable poly (D …
The effect of the oral administration of polymeric nanoparticles on the efficacy and toxicity of tamoxifen
The present investigation reports on the conditions for preparation of tamoxifen loaded
PLGA nanoparticles (Tmx-NPs) for oral administration. Tmx-NPs with> 85% entrapment …
PLGA nanoparticles (Tmx-NPs) for oral administration. Tmx-NPs with> 85% entrapment …
Tamoxifen-loaded poly (L-lactide) nanoparticles: development, characterization and in vitro evaluation of cytotoxicity
C Altmeyer, TK Karam, NM Khalil… - Materials Science and …, 2016 - Elsevier
In this study, poly (L-lactide)(PLA) nanoparticles containing Tamoxifen (Tmx) were
developed using an emulsion/solvent evaporation method, observing the influence of …
developed using an emulsion/solvent evaporation method, observing the influence of …
Cellular uptake and concentrations of tamoxifen upon administration in poly (ε-caprolactone) nanoparticles
JS Chawla, MM Amiji - Aaps Pharmsci, 2003 - Springer
Purpose: In an attempt to increase the local concentration of tamoxifen in estrogen receptor
positive breast cancer cells, we have prepared and characterized poly (ε …
positive breast cancer cells, we have prepared and characterized poly (ε …
Poly (ethylene oxide)-modified poly (ɛ-caprolactone) nanoparticles for targeted delivery of tamoxifen in breast cancer
DB Shenoy, MM Amiji - International journal of pharmaceutics, 2005 - Elsevier
This study was carried out to evaluate and compare the biodistribution profile of tamoxifen
when administered intravenously (iv) as a simple solution or when encapsulated in …
when administered intravenously (iv) as a simple solution or when encapsulated in …
Methotrexate and Curcumin co-encapsulated PLGA nanoparticles as a potential breast cancer therapeutic system: In vitro and in vivo evaluation
Nanoparticulate delivery systems have been noticed for chemotherapeutical delivery due to
their ability in controlling the drug release and reducing the side effect. These systems could …
their ability in controlling the drug release and reducing the side effect. These systems could …
Controlled release of tamoxifen citrate encapsulated in cross-linked guar gum nanoparticles
JK Sarmah, R Mahanta, SK Bhattacharjee… - International journal of …, 2011 - Elsevier
Natural polysaccharides, due to their outstanding merits, have received more and more
attention in the field of drug delivery. In the present study tamoxifen citrate, TMX (a non …
attention in the field of drug delivery. In the present study tamoxifen citrate, TMX (a non …
Revolutionizing anticancer drug delivery: Exploring the potential of tamoxifen-loaded nanoformulations
Tamoxifen (TAM), as a hydrophobic drug, is a selective estrogen modulator (SERM) applied
to hormone therapy for breast cancer (BC). Although it is effective and affordable in BC …
to hormone therapy for breast cancer (BC). Although it is effective and affordable in BC …
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