Tendon injury is the most common disease in the musculoskeletal system. The current
treatment methods have many limitations, such as poor therapeutic effects, functional loss of …

The objective of this study was to determine how in vitro mechanical stimulation of tissue
engineered constructs affects their stiffness and modulus in culture and tendon repair …

Tendons are mechanosensitive tissues that connect and transmit the forces generated by
muscles to bones by allowing the conversion of mechanical input into biochemical signals …

Background: Tendon and ligament injuries accounted for 30% of all musculoskeletal
consultations with 4 million new incidences worldwide each year and thus imposed a …

High tensile forces transmitted by tendons and ligaments make them susceptible to tearing
or complete rupture. The present standard reparative technique is the surgical implantation …

Over the past 8 years, our group has been continuously improving tendon repair using a
functional tissue engineering (FTE) paradigm. This paradigm was motivated by inconsistent …

Tendon disease is a significant and growing burden to healthcare systems. One strategy to
address this challenge is tissue engineering. A widely held view in this field is that …

Tendon injuries range from acute traumatic ruptures and lacerations to chronic overuse
injuries, such as tendinosis. Even with improved nonsurgical, surgical, and rehabilitation …

Engineered soft tissue products—both tendon and ligament—have gained tremendous
interest in regenerative medicine as alternatives to autograft and allograft treatments due to …

Background: There exists a range of surgical and non-surgical approaches to the treatment
of both acute and chronic tendon injuries. Despite surgical advances in the management of …