Thinking and acting beyond the positive: the role of the cognitive and negative symptoms in schizophrenia

M Carbon, CU Correll - CNS spectrums, 2014 - cambridge.org
Since currently available antipsychotic medications predominantly treat hallucinations,
delusions, disorganized thoughts and behavior, and related agitation/aggression, attention …

Negative symptoms of schizophrenia: clinical features, relevance to real world functioning and specificity versus other CNS disorders

G Foussias, O Agid, G Fervaha, G Remington - European …, 2014 - Elsevier
Negative symptoms have long been recognized as a central feature of the phenomenology
of schizophrenia, dating back to the early descriptions by Kraepelin and Bleuler. Over the …

Neuropsychology in schizophrenia: an update

AL Hoff, WS Kremen - Current Opinion in Psychiatry, 2003 - journals.lww.com
As a core symptom, neuropsychological dysfunction specific to the disorder must be
precisely defined and targeted for remediation if these patients are to be treated effectively …

[HTML][HTML] Negative symptoms in schizophrenia: Newly emerging measurements, pathways, and treatments

SR Marder, D Umbricht - Schizophrenia Research, 2023 - Elsevier
The negative symptoms of schizophrenia, which often appear earlier than any other
symptom, are prominent and clinically relevant in the majority of patients. As a result, interest …

Addressing the unmet needs of patients with persistent negative symptoms of schizophrenia: emerging pharmacological treatment options

P Chue, JK Lalonde - Neuropsychiatric disease and treatment, 2014 - Taylor & Francis
The negative symptoms of schizophrenia represent an impairment of normal emotional
responses, thought processes and behaviors, and include blunting or flattening of affect …

Neuropsychological abnormalities in schizophrenia and major mood disorders: similarities and differences

DM Barch - Current psychiatry reports, 2009 - Springer
The past 20 years have been witness to a growing knowledge base of research highlighting
the critical importance of cognition in understanding functional status and outcome in …

[HTML][HTML] Negative symptoms of schizophrenia: clinical characteristics, pathophysiological substrates, experimental models and prospects for improved treatment

MJ Millan, K Fone, T Steckler, WP Horan - European …, 2014 - Elsevier
Schizophrenia is a complex and multifactorial disorder generally diagnosed in young adults
at the time of the first psychotic episode of delusions and hallucinations. These positive …

Negative symptoms and cognitive impairments in schizophrenia: two key symptoms negatively influencing social functioning

K Kaneko - Yonago acta medica, 2018 - jstage.jst.go.jp
Schizophrenia is a chronic, disabling disorder, which commonly emerges in adolescence
and young adulthood. While pharmacological treatment with currently available second …

The negative symptoms of schizophrenia: a cognitive perspective

NA Rector, AT Beck, N Stolar - The Canadian Journal of …, 2005 - journals.sagepub.com
Recent reports of improvement in the negative symptoms of schizophrenia following
targeted cognitive interventions have prompted interest in the cognitive underpinnings of …

Cognitive deficits and functional outcome in schizophrenia

CR Bowie, PD Harvey - Neuropsychiatric disease and treatment, 2006 - Taylor & Francis
Cognitive dysfunction is a core feature of schizophrenia. Deficits are moderate to severe
across several domains, including attention, working memory, verbal learning and memory …