Cumulative risk evaluation of phthalates under TSCA
D Payne-Sturges, S De Saram… - … Science & Technology, 2023 - ACS Publications
The US Environmental Protection Agency (EPA) is currently conducting separate Toxic
Substances Control Act (TSCA) risk evaluations for seven phthalates: dibutyl phthalate …
Substances Control Act (TSCA) risk evaluations for seven phthalates: dibutyl phthalate …
Phthalate risks, phthalate regulation, and public health: a review
MA Kamrin - Journal of Toxicology and Environmental Health, Part …, 2009 - Taylor & Francis
As a result of concerns about the toxicity of phthalates to humans, several expert panels
were convened toward the end of the 1990s to evaluate the implications of the scientific …
were convened toward the end of the 1990s to evaluate the implications of the scientific …
Assessing human exposure to chemicals in materials, products and articles: the international risk management landscape for phthalates
CMA Eichler, EA Cohen Hubal… - Environmental science & …, 2019 - ACS Publications
Risk-based chemical safety assessments are increasingly being conducted to support
chemical management decisions and informed substitution to protect public health. Rapid …
chemical management decisions and informed substitution to protect public health. Rapid …
Integrating biomonitoring exposure data into the risk assessment process: phthalates [diethyl phthalate and di (2-ethylhexyl) phthalate] as a case study
AM Calafat, RH McKee - Environmental health perspectives, 2006 - ehp.niehs.nih.gov
The probability of nonoccupational exposure to phthalates is high given their use in a vast
range of consumables, including personal care products (eg, perfumes, lotions, cosmetics) …
range of consumables, including personal care products (eg, perfumes, lotions, cosmetics) …
Chemical activity–based environmental risk analysis of the plasticizer di‐ethylhexyl phthalate and its main metabolite mono‐ethylhexyl phthalate
FAPC Gobas, SV Otton, LF Tupper‐Ring… - Environmental …, 2017 - Wiley Online Library
The present study applies a chemical activity–based approach to: 1) evaluate environmental
concentrations of di‐ethylhexyl phthalate (DEHP; n= 23 651) and its metabolite mono …
concentrations of di‐ethylhexyl phthalate (DEHP; n= 23 651) and its metabolite mono …
An analysis of cumulative risks based on biomonitoring data for six phthalates using the Maximum Cumulative Ratio
JM Reyes, PS Price - Environment international, 2018 - Elsevier
Abstract The Maximum Cumulative Ratio (MCR) quantifies the degree to which a single
chemical drives the cumulative risk of an individual exposed to multiple chemicals …
chemical drives the cumulative risk of an individual exposed to multiple chemicals …
Assessment of chemical coexposure patterns based upon phthalate biomonitoring data within the 2007/2008 National Health and Nutrition Examination Survey
H Qian, M Chen, KM Kransler, RT Zaleski - Journal of exposure science …, 2015 - nature.com
As regulatory initiatives increasingly call for an understanding of the cumulative risks from
chemical mixtures, evaluating exposure data from large biomonitoring programs, which may …
chemical mixtures, evaluating exposure data from large biomonitoring programs, which may …
Assessment of phthalates/phthalate alternatives in children's toys and childcare articles: Review of the report including conclusions and recommendation of the …
PJ Lioy, R Hauser, C Gennings, HM Koch… - Journal of exposure …, 2015 - nature.com
Abstract The Consumer Product Safety Commission (CPSC) convened a Chronic Hazard
Advisory Panel (CHAP) on Phthalates found in children's toys, and childcare products, and …
Advisory Panel (CHAP) on Phthalates found in children's toys, and childcare products, and …
Temporal trends in exposures to six phthalates from biomonitoring data: implications for cumulative risk
JM Reyes, PS Price - Environmental science & technology, 2018 - ACS Publications
Phthalates are used in a wide range of consumer goods, resulting in exposures to specific
phthalates that vary over time in accordance with changes in product use and how …
phthalates that vary over time in accordance with changes in product use and how …
Generation of hazard indices for cumulative exposure to phthalates for use in cumulative risk assessment
KLY Christensen, SL Makris, M Lorber - Regulatory Toxicology and …, 2014 - Elsevier
Exposures to multiple chemicals may contribute to increased risk of similar adverse effects.
Cumulative risk may be estimated using a hazard index (HI), the sum of individual hazard …
Cumulative risk may be estimated using a hazard index (HI), the sum of individual hazard …