Histochemical and histomorphological evidence of the modulating role of 1-isothiocyanate-4-methyl sulfonyl butane on cisplatin-induced testicular-pituitary axis …

SA Adelakun, OW Akintunde, B Ogunlade… - Morphologie, 2023 - Elsevier
Background This study examine the histochemical and histomorphological effect of 1-
isothiocyanato-4-methyl sulfonyl butane (SFN) on cisplatin (CP) induced testicular alteration …

[HTML][HTML] Ameliorating and protective potential of 1-isothiocyanato-4-methyl sulfonyl butane on cisplatin induced oligozoospermia and testicular dysfunction via redox …

SA Adelakun, OW Akintunde, SO Jeje, OA Alao - Phytomedicine Plus, 2022 - Elsevier
Abstract Background 1-isothiocyanato-4-methyl-sulfonyl (SFN) butane is a naturally
occurring compound from broccoli. Cisplatin (CP) reported has a standard …

Assessment of the effect of sodium hydrogen sulfide (hydrogen sulfide donor) on cisplatin-induced testicular toxicity in rats

N Azarbarz, Z Shafiei Seifabadi, MZ Moaiedi… - … Science and Pollution …, 2020 - Springer
Cisplatin (CIS) is an antineoplastic drug able to produce free radicals that are capable to
induce various side effects in different tissues. Hydrogen sulfide (H 2 S) has notable …

[PDF][PDF] Ameliorative effect of thiamine pyrophosphate against cisplatin-induced reproductive system damage within male rats

MAA Mnati, BAR Mshimesh, MM Ibraheem… - Sys Rev …, 2020 - researchgate.net
Background: Cisplatin considers one of the most potent antineoplastic drugs that manage
solid and germ cell cancer. The major drawback in cisplatin treatment is infertility. Thiamine …

[HTML][HTML] Effect of monosodium glutamate on testicular tissue of paclitaxel-treated mice: An experimental study

D Kianifard, A Ehsani, PZ Daneshgar… - International Journal …, 2019 - ncbi.nlm.nih.gov
Background Paclitaxel (PTX), a chemotherapeutic agent, and monosodium glutamate (MSG)
have oxidative effects on testicular tissue. Objective In this study, the effects of MSG …

Tert-butylhydroquinone preserve testicular steroidogenesis and spermatogenesis in cisplatin-intoxicated rats by targeting oxidative stress, inflammation and apoptosis

VU Nna, GA Ujah, JB Suleiman, M Mohamed… - Toxicology, 2020 - Elsevier
Cisplatin (Cis) is an effective chemotherapeutic intervention against many cancer types.
However, the oxidative stress-related toxicities associated with cancer cell resistance …

Sinapic acid ameliorates cisplatin‐induced disruptions in testicular steroidogenesis and spermatogenesis by modulating androgen receptor, proliferating cell nuclear …

M Demir, F Altındağ - Andrologia, 2022 - Wiley Online Library
The chemotherapeutic cisplatin, which is widely used in many cancer types, causes
testicular toxicity. Sinapic acid has many therapeutic effects such as antioxidant, anti …

[PDF][PDF] Captopril and telmisartan ameliorate cisplatin-induced testicular damage in rats via anti-inflammatory and antioxidant pathways

AH Eid, NF Abdelkader, OMA El-Raouf… - International Journal of …, 2016 - Citeseer
Despite the prevalent clinical applications of cisplatin, serious toxic side effects comprising
reproductive toxicity confine its therapeutic efficacy. Thus, the current study explored the …

Protective effect of curcumin in cisplatin-induced oxidative injury in rat testis: mitogen-activated protein kinase and nuclear factor-kappa B signaling pathways

YO Ilbey, E Ozbek, M Cekmen, A Simsek… - Human …, 2009 - academic.oup.com
BACKGROUND The aim of this study was to investigate the cellular/biochemical
mechanisms by which cisplatin (CIS) causes testicular toxicity. We evaluated the role of …

Protective effects of sinapic acid against cyclophosphamide‐induced testicular toxicity via inhibiting oxidative stress, caspase‐3 and NF‐kB activity in BALB/c mice

S Rezaei, SJ Hosseinimehr, M Zargari… - Andrologia, 2021 - Wiley Online Library
Cyclophosphamide (CP), as a chemotherapeutic agent, with the generation of oxidative
stress leads to testicular toxicity. Sinapic acid (SA), as a phenylpropanoid compound has …