Spatial patterns and frequency distributions of regional deformation in the healthy human lung

DE Hurtado, N Villarroel, C Andrade, J Retamal… - … and modeling in …, 2017 - Springer
Understanding regional deformation in the lung has long attracted the medical community,
as parenchymal deformation plays a key role in respiratory physiology. Recent advances in …

Three-dimensional characterization of regional lung deformation

R Amelon, K Cao, K Ding, GE Christensen… - Journal of …, 2011 - Elsevier
The deformation of the lung during inspiration and expiration involves regional variations in
volume change and orientational preferences. Studies have reported techniques for …

Assessment of regional non-linear tissue deformation and air volume change of human lungs via image registration

N Jahani, Y Yin, EA Hoffman, CL Lin - Journal of biomechanics, 2014 - Elsevier
We evaluate the non-linear characteristics of the human lung via image registration-derived
local variables based on volumetric multi-detector-row computed tomographic (MDCT) lung …

[HTML][HTML] Correlating local volumetric tissue strains with global lung mechanics measurements

H Arora, RL Mitchell, R Johnston, M Manolesos… - Materials, 2021 - mdpi.com
The mechanics of breathing is a fascinating and vital process. The lung has complexities
and subtle heterogeneities in structure across length scales that influence mechanics and …

Improving the accuracy of registration-based biomechanical analysis: a finite element approach to lung regional strain quantification

DE Hurtado, N Villarroel, J Retamal… - … on Medical Imaging, 2015 - ieeexplore.ieee.org
Tissue deformation plays an important role in lung physiology, as lung parenchyma largely
deforms during spontaneous ventilation. However, excessive regional deformation may lead …

Modeling real-time 3-D lung deformations for medical visualization

AP Santhanam, C Imielinska… - IEEE Transactions …, 2008 - ieeexplore.ieee.org
In this paper, we propose a physics-based and physiology-based approach for modeling
real-time deformations of 3-D high-resolution polygonal lung models obtained from high …

Towards a model of lung biomechanics: pulmonary kinematics via registration of serial lung images

TA Sundaram, JC Gee - Medical image analysis, 2005 - Elsevier
The lungs are highly elastic organs, composed of a variety of structures: vasculature,
airways and parenchyma. The unique mechanical properties of each of these structures …

Estimation and validation of patient‐specific high‐resolution lung elasticity derived from 4DCT

K Hasse, D O'Connell, Y Min, J Neylon… - Medical …, 2018 - Wiley Online Library
Purpose Lung diseases are commonly associated with changes in lung tissue's
biomechanical properties. Functional imaging techniques, such as elastography, have …

[HTML][HTML] Novel Mechanical Strain Characterization of Ventilated ex vivo Porcine and Murine Lung using Digital Image Correlation

CA Mariano, S Sattari, M Maghsoudi-Ganjeh… - Frontiers in …, 2020 - frontiersin.org
Respiratory illnesses, such as bronchitis, emphysema, asthma, and COVID-19, substantially
remodel lung tissue, deteriorate function, and culminate in a compromised breathing ability …

Registration-based regional lung mechanical analysis: retrospectively reconstructed dynamic imaging versus static breath-hold image acquisition

K Ding, K Cao, GE Christensen… - Medical Imaging …, 2009 - spiedigitallibrary.org
The lungs undergo expansion and contraction during the respiratory cycle. Since many
disease or injury conditions are associated with the biomechanical or material property …