Francisella tularensis, the causative agent of tularemia, lacks typical bacterial virulence
factors and toxins but still exhibits extreme virulence. The bacterial multidrug efflux systems …

The Gram-negative bacterium Francisella tularensis is the causative agent of tularemia.
Interest in this zoonotic pathogen has increased due to its classification as a category A …

Francisella tularensis is a Gram-negative bacterium that causes a fatal human disease
known as tularemia. The Centers for Disease Control and Prevention have classified F …

Francisella tularensis is a highly infectious bacterium causing the zoonotic disease
tularemia. This facultative intracellular bacterium replicates in vivo mainly inside …

The essential mechanisms and virulence factors enabling Francisella species to replicate
inside host macrophages are not fully understood. Methionine sulfoxide reductase (Msr) is …

Francisella tularensis is a Gram-negative, facultative intracellular pathogen and the
causative agent of tularemia. Previous studies with the attenuated live vaccine strain (LVS) …

Francisella tularensis is an intracellular bacterium and as such is expected to encounter a
continuous attack by reactive oxygen species (ROS) in its intracellular habitat and efficiently …

Francisella tularensis is a facultative intracellular pathogen. Its capacity to induce disease
depends on the ability to invade and multiply within a wide range of eukaryotic cells, such as …

Francisella tularensis causes a lethal human disease known as tularemia. As an
intracellular pathogen, Francisella survives and replicates in phagocytic cells, such as …

Francisella tularensis, the causative agent of a fatal human disease known as tularemia, has
been used in the bioweapon programs of several countries in the past, and now it is …