Detecting natural selection in genomic data
JJ Vitti, SR Grossman, PC Sabeti - Annual review of genetics, 2013 - annualreviews.org
The past fifty years have seen the development and application of numerous statistical
methods to identify genomic regions that appear to be shaped by natural selection. These …
methods to identify genomic regions that appear to be shaped by natural selection. These …
Thinking too positive? Revisiting current methods of population genetic selection inference
C Bank, GB Ewing, A Ferrer-Admettla, M Foll… - Trends in Genetics, 2014 - cell.com
In the age of next-generation sequencing, the availability of increasing amounts and
improved quality of data at decreasing cost ought to allow for a better understanding of how …
improved quality of data at decreasing cost ought to allow for a better understanding of how …
Interrogating a high-density SNP map for signatures of natural selection
Identifying genomic regions that have been targets of natural selection remains one of the
most important and challenging areas of research in genetics. To this end, we report an …
most important and challenging areas of research in genetics. To this end, we report an …
[HTML][HTML] Population history and natural selection shape patterns of genetic variation in 132 genes
Identifying regions of the human genome that have been targets of natural selection will
provide important insights into human evolutionary history and may facilitate the …
provide important insights into human evolutionary history and may facilitate the …
A genome scan to detect candidate regions influenced by local natural selection in human populations
M Kayser, S Brauer, M Stoneking - Molecular Biology and …, 2003 - academic.oup.com
As human populations dispersed throughout the world, they were subjected to new selective
forces, which must have led to local adaptation via natural selection and hence altered …
forces, which must have led to local adaptation via natural selection and hence altered …
Molecular signatures of natural selection
R Nielsen - Annu. Rev. Genet., 2005 - annualreviews.org
There is an increasing interest in detecting genes, or genomic regions, that have been
targeted by natural selection. The interest stems from a basic desire to learn more about …
targeted by natural selection. The interest stems from a basic desire to learn more about …
Recent and ongoing selection in the human genome
The recent availability of genome-scale genotyping data has led to the identification of
regions of the human genome that seem to have been targeted by selection. These findings …
regions of the human genome that seem to have been targeted by selection. These findings …
1000 Genomes Selection Browser 1.0: a genome browser dedicated to signatures of natural selection in modern humans
M Pybus, GM Dall'Olio, P Luisi, M Uzkudun… - Nucleic acids …, 2014 - academic.oup.com
Searching for Darwinian selection in natural populations has been the focus of a multitude of
studies over the last decades. Here we present the 1000 Genomes Selection Browser 1.0 …
studies over the last decades. Here we present the 1000 Genomes Selection Browser 1.0 …
Genomic signatures of positive selection in humans and the limits of outlier approaches
Identifying regions of the human genome that have been targets of positive selection will
provide important insights into recent human evolutionary history and may facilitate the …
provide important insights into recent human evolutionary history and may facilitate the …
Detecting the form of selection from DNA sequence data
SP Otto - Trends in Genetics, 2000 - cell.com
Clues to our evolutionary history lie hidden within DNA sequence data. One of the great
challenges facing population geneticists is to identify and accurately interpret these clues …
challenges facing population geneticists is to identify and accurately interpret these clues …