[HTML][HTML] Prebiotic administration normalizes lipopolysaccharide (LPS)-induced anxiety and cortical 5-HT2A receptor and IL1-β levels in male mice

HM Savignac, Y Couch, M Stratford… - Brain, behavior, and …, 2016 - Elsevier
The manipulation of the enteric microbiota with specific prebiotics and probiotics, has been
shown to reduce the host's inflammatory response, alter brain chemistry, and modulate …

The prebiotics 3′ Sialyllactose and 6′ Sialyllactose diminish stressor-induced anxiety-like behavior and colonic microbiota alterations: Evidence for effects on the …

AJ Tarr, JD Galley, SE Fisher, M Chichlowski… - Brain, behavior, and …, 2015 - Elsevier
There are extensive bidirectional interactions between the gut microbiota and the central
nervous system (CNS), and studies demonstrate that stressor exposure significantly alters …

Sex difference in prebiotics on gut and blood–brain barrier dysfunction underlying stress‐induced anxiety and depression

J Jiang, Y Fu, A Tang, X Gao, D Zhang… - CNS Neuroscience …, 2023 - Wiley Online Library
Background Most of the previous studies have demonstrated the potential antidepressive
and anxiolytic role of prebiotic supplement in male subjects, yet few have females enrolled …

Oral treatment with Lactobacillus rhamnosus attenuates behavioural deficits and immune changes in chronic social stress

A Bharwani, MF Mian, MG Surette, J Bienenstock… - BMC medicine, 2017 - Springer
Background Stress-related disorders involve systemic alterations, including disruption of the
intestinal microbial community. Given the putative connections between the microbiota …

Gut emotions-mechanisms of action of probiotics as novel therapeutic targets for depression and anxiety disorders

A Slyepchenko, AF Carvalho, DS Cha… - CNS & Neurological …, 2014 - ingentaconnect.com
A priority clinical and research agenda in mood and anxiety disorders is to identify
determinants that influence illness trajectory and outcome. Over the past decade, studies …

Targeting the microbiota-gut-brain axis: prebiotics have anxiolytic and antidepressant-like effects and reverse the impact of chronic stress in mice

A Burokas, S Arboleya, RD Moloney, VL Peterson… - Biological …, 2017 - Elsevier
Background The realization that the microbiota-gut-brain axis plays a critical role in health
and disease, including neuropsychiatric disorders, is rapidly advancing. Nurturing a …

Ingestion of probiotic (Lactobacillus helveticus and Bifidobacterium longum) alters intestinal microbial structure and behavioral expression following social defeat …

KA Partrick, AM Rosenhauer, J Auger, AR Arnold… - Scientific Reports, 2021 - nature.com
Social stress exacerbates anxious and depressive behaviors in humans. Similarly, anxiety-
and depressive-like behaviors are triggered by social stress in a variety of non-human …

Effects of Lactobacillus helveticus on murine behavior are dependent on diet and genotype and correlate with alterations in the gut microbiome

CL Ohland, L Kish, H Bell, A Thiesen, N Hotte… - …, 2013 - Elsevier
Modulation of the gut microbiota with diet and probiotic bacteria can restore intestinal
homeostasis in inflammatory conditions and alter behavior via the gut–brain axis. The …

Probiotic consumption during puberty mitigates LPS-induced immune responses and protects against stress-induced depression-and anxiety-like behaviors in …

E Murray, R Sharma, KB Smith, KD Mar, R Barve… - Brain, Behavior, and …, 2019 - Elsevier
Puberty/adolescence is a significant period of development and a time with a high
emergence of psychiatric disorders. During this period, there is increased neuroplasticity …

Probiotic supplementation can positively affect anxiety and depressive symptoms: a systematic review of randomized controlled trials

M Pirbaglou, J Katz, RJ de Souza, JC Stearns… - Nutrition research, 2016 - Elsevier
Gastrointestinal microbiota, consisting of microbial communities in the gastrointestinal tract,
play an important role in digestive, metabolic, and immune functioning. Preclinical studies …