Global hippocampal and selective thalamic nuclei atrophy differentiate chronic TBI from Non-TBI

J Sandry, E Dobryakova - Cortex, 2021 - Elsevier
Traumatic brain injury (TBI) may increase susceptibility to neurodegenerative diseases later
in life. One neurobiological parallel between chronic TBI and neurodegeneration may be …

Distinct patterns of neurodegeneration after TBI and in Alzheimer's disease

NSN Graham, JH Cole, NJ Bourke… - Alzheimer's & …, 2023 - Wiley Online Library
Introduction Traumatic brain injury (TBI) is a dementia risk factor, with Alzheimer's disease
(AD) more common following injury. Patterns of neurodegeneration produced by TBI can be …

Spatiotemporal profile of atrophy in the first year following moderate‐severe traumatic brain injury

DJ Brennan, J Duda, JB Ware, J Whyte… - Human Brain …, 2023 - Wiley Online Library
Traumatic brain injury (TBI) triggers progressive neurodegeneration resulting in brain
atrophy that continues months‐to‐years following injury. However, a comprehensive …

Acute cognitive impairment after traumatic brain injury predicts the occurrence of brain atrophy patterns similar to those observed in Alzheimer's disease

KA Rostowsky, A Irimia… - GeroScience, 2021 - Springer
Traumatic brain injuries (TBIs) are often followed by persistent structural brain alterations
and by cognitive sequalae, including memory deficits, reduced neural processing speed …

Significant acceleration of regional brain aging and atrophy after mild traumatic brain injury

AF Shida, RJ Massett, P Imms… - The Journals of …, 2023 - academic.oup.com
Brain regions' rates of age-related volumetric change after traumatic brain injury (TBI) are
unknown. Here, we quantify these rates cross-sectionally in 113 persons with recent mild …

Cognitive function and brain structure after recurrent mild traumatic brain injuries in young-to-middle-aged adults

J List, S Ott, M Bukowski, R Lindenberg… - Frontiers in human …, 2015 - frontiersin.org
Recurrent mild traumatic brain injuries (mTBIs) are regarded as an independent risk factor
for developing dementia in later life. We here aimed to evaluate associations between …

Assessing the relationship between neurocognitive performance and brain volume in chronic moderate–severe traumatic brain injury

N Konstantinou, E Pettemeridou, I Seimenis… - Frontiers in …, 2016 - frontiersin.org
Objectives Characterize the scale and pattern of long-term atrophy in gray matter (GM),
white matter (WM), and cerebrospinal fluid (CSF) in chronic moderate–severe traumatic …

Brain neurodegeneration in the chronic stage of the survivors from severe non-missile traumatic brain injury: a voxel-based morphometry within-group at one versus …

F Tomaiuolo, A Cerasa, JP Lerch, U Bivona… - Journal of …, 2021 - liebertpub.com
The long-term time course of neuropathological changes occurring in survivors from severe
traumatic brain injury (TBI) remains uncertain. We investigated the brain morphometry and …

History of traumatic brain injury is associated with increased grey-matter loss in patients with mild cognitive impairment

MA Khoury, NW Churchill, A Di Battista, SJ Graham… - Journal of …, 2024 - Springer
Objectives To investigate whether a history of traumatic brain injury (TBI) is associated with
greater long-term grey-matter loss in patients with mild cognitive impairment (MCI). Methods …

Scale and pattern of atrophy in the chronic stages of moderate-severe TBI

REA Green, B Colella, JJ Maller, M Bayley… - Frontiers in human …, 2014 - frontiersin.org
Background: Moderate-severe traumatic brain injury (TBI) is increasingly being understood
as a progressive disorder, with growing evidence of reduced brain volume and white matter …