The mechanisms of action of NSAIDs in analgesia
JN Cashman - Drugs, 1996 - Springer
Traditionally, the analgesic action of nonsteroidal anti-inflammatory drugs (NSAIDs) has
been explained on the basis of their inhibition of the enzymes that synthesise …
been explained on the basis of their inhibition of the enzymes that synthesise …
Mechanism of action of nonsteroidal anti-inflammatory drugs
JR Vane, RM Botting - The American journal of medicine, 1998 - Elsevier
Salicylic acid and salicylates, obtained from natural sources, have long been used as
medicaments. Salicylic acid was chemically synthesized in 1860 and was used as an …
medicaments. Salicylic acid was chemically synthesized in 1860 and was used as an …
Non-steroidal anti-inflammatory drugs: an overview
K Jahnavi, PP Reddy, B Vasudha… - Journal of Drug Delivery …, 2019 - jddtonline.info
Non-steroidal anti-inflammatory drugs (NSAIDs) including both traditional non-selective
NSAIDs and the selective cyclooxygenase (COX)-2 inhibitors, are widely used for their anti …
NSAIDs and the selective cyclooxygenase (COX)-2 inhibitors, are widely used for their anti …
Profile and mechanisms of gastrointestinal and other side effects of nonsteroidal anti-inflammatory drugs (NSAIDs)
KD Rainsford - The American journal of medicine, 1999 - Elsevier
The popular view that all nonsteroidal anti-inflammatory drugs (NSAIDs) act by inhibiting the
production of prostaglandins has been challenged by the discovery that they also affect a …
production of prostaglandins has been challenged by the discovery that they also affect a …
Nonsteroidal anti-inflammatory drugs in perisurgical pain management: mechanisms of action and rationale for optimum use
J Cashman, G McAnulty - Drugs, 1995 - Springer
Nonsteroidal anti-inflammatory drugs (NSAIDs) are a group of agents with similar actions but
diverse chemical structures. Aspirin (acetylsalicylic acid) and sodium salicylate were the first …
diverse chemical structures. Aspirin (acetylsalicylic acid) and sodium salicylate were the first …
Mechanism of action of aspirin-like drugs
JR Vane, RM Botting - Seminars in arthritis and rheumatism, 1997 - Elsevier
Nonsteroid antiinflammatory drugs (NSAIDs) or aspirin-like drugs act by inhibiting the activity
of the cyclooxygenase (COX) enzyme. Two isoforms of COX exist, COX-1, which is …
of the cyclooxygenase (COX) enzyme. Two isoforms of COX exist, COX-1, which is …
New insights into the use of currently available non-steroidal anti-inflammatory drugs
K Brune, P Patrignani - Journal of pain research, 2015 - Taylor & Francis
Non-steroidal anti-inflammatory drugs (NSAIDs), which act via inhibition of the
cyclooxygenase (COX) isozymes, were discovered more than 100 years ago. They remain a …
cyclooxygenase (COX) isozymes, were discovered more than 100 years ago. They remain a …
COX-dependent mechanisms involved in the antinociceptive action of NSAIDs at central and peripheral sites
M Burian, G Geisslinger - Pharmacology & therapeutics, 2005 - Elsevier
Despite the diverse chemical structure of aspirin-like drugs, the antinociceptive effect of
NSAIDs is mainly due to their common property of inhibiting cyclooxygenases involved in …
NSAIDs is mainly due to their common property of inhibiting cyclooxygenases involved in …
Variability in the response to non‐steroidal anti‐inflammatory drugs: mechanisms and perspectives
A Bruno, S Tacconelli… - Basic & clinical …, 2014 - Wiley Online Library
Non‐steroidal anti‐inflammatory drugs (NSAID s) are a chemically heterogeneous group of
compounds that provide unmistakable and significant health benefits in the treatment of pain …
compounds that provide unmistakable and significant health benefits in the treatment of pain …
Dual acting anti-inflammatory drugs: a reappraisal
A Bertolini, A Ottani, M Sandrini - Pharmacological Research, 2001 - Elsevier
Rheumatic diseases are the most prevalent causes of disability in western countries, and
non-steroidal anti-inflammatory drugs (NSAIDs) are still the most commonly used remedies …
non-steroidal anti-inflammatory drugs (NSAIDs) are still the most commonly used remedies …