Antineoplastic chemotherapies are particularly efficient when they elicit immunogenic cell
death, thus provoking an anticancer immune response. Here we demonstrate that …

One particular strategy to render anticancer therapies efficient consists of converting the
patient's own tumor cells into therapeutic vaccines, via the induction of immunogenic cell …

The rising success of cancer immunotherapy has produced immense interest in defining the
clinical contexts that may benefit from this therapeutic approach. To this end, there is a need …

Autophagy, a cellular waste disposal process, has well-established tumor-suppressive
properties. New studies indicate that, in addition to its cell-autonomous anti-tumorigenic …

Autophagy is a genetically well-controlled cellular process that is tightly controlled by a set of
core genes, including the family of autophagy-related genes (ATG). Autophagy is a “double …

Autophagy is quintessential for the maintenance of cellular homeostasis in all eukaryotic
cells, explaining why both normal and malignant cells benefit from proficient autophagic …

Although T cell checkpoint inhibitors have transformed the treatment of cancer, the
molecular determinants of tumor cell sensitivity to T cell–mediated killing need further …

Autophagy is fundamental to the maintenance of intracellular homeostasis in virtually all
human cells. Accordingly, defective autophagy predisposes healthy cells to undergoing …

Macroautophagy (hereafter autophagy) degrades and recycles intracellular components to
sustain metabolism and survival during starvation. Host autophagy promotes tumor growth …

Basal autophagy plays a critical role in maintaining cellular homeostasis and genomic
integrity by degrading aged or malfunctioning organelles and damaged or misfolded …