Molecular mechanism operating in animal models of neurogenic detrusor overactivity: A systematic review focusing on bladder dysfunction of neurogenic origin
A Ferreira, D Nascimento, CD Cruz - International Journal of Molecular …, 2023 - mdpi.com
Neurogenic detrusor overactivity (NDO) is a severe lower urinary tract disorder,
characterized by urinary urgency, retention, and incontinence, as a result of a neurologic …
characterized by urinary urgency, retention, and incontinence, as a result of a neurologic …
Detrusor underactivity: a plea for new approaches to a common bladder dysfunction
GA Van Koeveringe, B Vahabi… - Neurourology and …, 2011 - Wiley Online Library
Aims Detrusor underactivity (DU) is defined by the International Continence Society as a
contraction of reduced strength and/or duration resulting in prolonged or incomplete …
contraction of reduced strength and/or duration resulting in prolonged or incomplete …
A ventral root avulsion injury model for neurogenic underactive bladder studies
HH Chang, LA Havton - Experimental neurology, 2016 - Elsevier
Detrusor underactivity (DU) is defined as a contraction of reduced strength and/or duration
during bladder emptying and results in incomplete and prolonged bladder emptying. The …
during bladder emptying and results in incomplete and prolonged bladder emptying. The …
Nerve sprouting and neurogenic inflammation characterize the neurogenic detrusor overactive bladder of patients no longer responsive to drug therapies
C Traini, G Del Popolo… - Journal of Cellular …, 2019 - Wiley Online Library
Abstract Urothelium and Lamina Propria (LP) are considered an integrate sensory system
which is able to control the detrusor activity. Complete supra‐sacral spinal cord lesions …
which is able to control the detrusor activity. Complete supra‐sacral spinal cord lesions …
Functional and molecular characterisation of the bilateral pelvic nerve crush injury rat model for neurogenic detrusor underactivity
K Dewulf, E Weyne, T Gevaert, Y Deruyver… - BJU …, 2019 - Wiley Online Library
Objectives To create a rat model for neurogenic detrusor underactivity (DU) by bilateral
pelvic nerve crush injury (BPNI) and to study temporal changes in detrusor contractility and …
pelvic nerve crush injury (BPNI) and to study temporal changes in detrusor contractility and …
Pharmacological and genetic analysis of mechanisms underlying detrusor overactivity in rats
O Yokoyama - … and Urodynamics: Official Journal of the …, 2010 - Wiley Online Library
Aims Suprapontine lesions, such as those resulting from cerebrovascular disease, cause
bladder storage dysfunction. Detrusor overactivity (DO) following cerebral infarction may be …
bladder storage dysfunction. Detrusor overactivity (DO) following cerebral infarction may be …
Molecular characterization of non-neurogenic and neurogenic lower urinary tract dysfunction (LUTD) in SCI-induced and partial bladder outlet obstruction mouse …
M von Siebenthal, A Akshay, M Besic… - International journal of …, 2023 - mdpi.com
We examined bladder function following spinal cord injury (SCI) by repeated urodynamic
investigation (UDI), including external urethral sphincter (EUS) electromyography (EMG) in …
investigation (UDI), including external urethral sphincter (EUS) electromyography (EMG) in …
Dysfunctional voiding behavior and impaired muscle contractility in a rat model of detrusor underactivity
EJ Gonzalez, MR Odom, JL Hannan… - Neurourology and …, 2021 - Wiley Online Library
Aims Detrusor underactivity (DU) is an understudied health concern with inadequate clinical
management. The pathophysiology of DU is unclear, and current therapies fail to improve …
management. The pathophysiology of DU is unclear, and current therapies fail to improve …
Neurogenic causes of detrusor underactivity
BT Kadow, P Tyagi, CJ Chermansky - Current bladder dysfunction reports, 2015 - Springer
Detrusor underactivity (DU) is a poorly understood dysfunction of the lower urinary tract
which arises from multiple etiologies. Symptoms of DU are non-specific, and a pressure-flow …
which arises from multiple etiologies. Symptoms of DU are non-specific, and a pressure-flow …
CNS involvement in overactive bladder: pathophysiology and opportunities for pharmacological intervention
KE Andersson, R Pehrson - Drugs, 2003 - Springer
The pathophysiology of overactive bladder (OAB) syndrome is complex, and involves both
peripheral and CNS factors. Several CNS disorders are associated with OAB, eg stroke …
peripheral and CNS factors. Several CNS disorders are associated with OAB, eg stroke …
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