We engineered a monoclonal antibody (mAb) against the human C-terminus of angiotensin-
(1–12)[h-Ang-(1–12)] and performed a biochemical characterization in concert with direct in …

Angiotensin-(1-12)[ANG-(1-12)] is a newly identified peptide detected in a variety of rat
tissues, including the brain. To determine whether brain ANG-(1-12) participates in blood …

Lack of specific antagonists to the amino-terminal heptapeptide angiotensin-(1-7)[Ang-(1-7)]
prompted us to evaluate the central effects of delivering a specific affinity-purified Ang-(1-7) …

Observations that angiotensin-(1-7)[ANG-(1-7)] may oppose the vasoconstrictor actions of
angiotensin II (ANG II) prompted an investigation of the effects of the heptapeptide on the …

In the present study, we reassessed whether angiotensin (Ang)-(1–7) can exert short-and
long-term cardiovascular effects because there has been a resurgence of interest in this N …

A low expression of angiotensinogen in the heart has been construed as indicating a
circulating uptake mechanism to explain the local effects of angiotensin II on tissues. The …

Abstract Angiotensin (Ang)-(1-7) is a bioactive component of the renin-angiotensin system
that is formed endogenously from either Ang I or Ang II. The first actions described for Ang-(1 …

During the last decade, knowledge of the actions of the various angiotensin peptides on the
cardiovascular system has dramatically increased. In addition to angiotensin II, the actions of …

BACKGROUND: Angiotensin-(1-12), measured by a self-developed, polyclonal antibody-
based radioimmunoassay, has been suggested to act as an alternative precursor of …

Abstract Angiotensin-(1–9)[Ang-(1–9)] is a peptide of the non-canonical renin-angiotensin
system (RAS) synthesized from angiotensin I by the monopeptidase angiotensin-converting …