Drug development, Brazilian biodiversity and political choices: Where are we heading?

PMP Ferreira, DDR Arcanjo… - Journal of Toxicology and …, 2023 - Taylor & Francis
The aim of this review was to (i) acknowledge structural advantages of natural products
(NPs) for designing therapeutic drugs;(ii) emphasize how wildlife conservation is socially …

The role of natural products in modern drug discovery.

JB Calixto - Anais da Academia Brasileira de Ciências, 2019 - SciELO Brasil
The global medicine market is about 1.1 trillion US dollars. About 35 percent of medicines
have originated from natural products. Brazil presents the largest biodiversity in the world …

The potential contribution of the natural products from Brazilian biodiversity to bioeconomy

M Valli, HM Russo, VS Bolzani - Anais da Academia Brasileira de …, 2018 - SciELO Brasil
The development of our society has been based on the use of biodiversity, especially for
medicines and nutrition. Brazil is the nation with the largest biodiversity in the world …

Natural products in drug discovery: impacts and opportunities—an assessment

G Brahmachari - … natural products: opportunities and challenges in …, 2012 - World Scientific
Nature stands as an inexhaustible source of novel chemotypes and pharmacophores, and
has been a source of medicinal agents for thousands of years, and an impressive number of …

Natural products in drug discovery–creating a new vision

GA Cordell - Phytochemistry Reviews, 2002 - Springer
Abstract “If only they had chosen to develop natural product drugs in a sustainable manner
at the turn of the century”. In 2050, when the Earth has a population of at least 9 billion, will …

Natural products: perspectives and challenges for use of Brazilian plant species in the bioeconomy

M Valli, VS Bolzani - Anais da Academia Brasileira de Ciências, 2019 - SciELO Brasil
The development of our society has been based on the use of biodiversity, especially for
nutrition, medicines and beauty. Brazil is the nation with the largest biodiversity in the world …

Challenges and rewards of research in marine natural products chemistry in Brazil

RGS Berlinck, E Hajdu, RM da Rocha… - Journal of Natural …, 2004 - ACS Publications
Brazil is blessed with a great biodiversity, which constitutes one of the most important
sources of biologically active compounds, even if it has been largely underexplored. As is …

[HTML][HTML] Pharmaceuticals from natural products: current trends

PR Seidl - Anais da Academia Brasileira de Ciências, 2002 - SciELO Brasil
The use of products extracted from plants for medicinal purposes can be traced to the
beginnings of civilization and up until the end of the nineteenth century natural products …

Medicinal plants in Brazil: Pharmacological studies, drug discovery, challenges and perspectives

RC Dutra, MM Campos, ARS Santos… - Pharmacological research, 2016 - Elsevier
This review article focuses on pre-clinical and clinical studies with some selected Brazilian
medicinal plants in different areas of interest, conducted by research groups in Brazil and …

Development of a natural products database from the biodiversity of Brazil

M Valli, RN Dos Santos, LD Figueira… - Journal of natural …, 2013 - ACS Publications
We describe herein the design and development of an innovative tool called the NuBBE
database (NuBBEDB), a new Web-based database, which incorporates several classes of …