The emerging role of autophagy as a target of environmental pollutants: an update on mechanisms
Autophagy is an evolutionarily conserved cellular system crucial for cellular homeostasis
that protects cells from a broad range of internal and extracellular stresses. Autophagy …
that protects cells from a broad range of internal and extracellular stresses. Autophagy …
Autophagy role in environmental pollutants exposure
GG Martínez-García, G Mariño - Progress in molecular biology and …, 2020 - Elsevier
During the last decades, the potential harmfulness derived from the exposure to
environmental pollutants has been largely demonstrated, with associated damages ranging …
environmental pollutants has been largely demonstrated, with associated damages ranging …
Autophagy in exposure to environmental chemicals
M Pesonen, K Vähäkangas - Toxicology Letters, 2019 - Elsevier
Autophagy is a catabolic pathway, which breaks down old and damaged cytoplasmic
material into basic biomolecules through lysosome-mediated digestion thereby recycling …
material into basic biomolecules through lysosome-mediated digestion thereby recycling …
Autophagy in toxicology: self‐consumption in times of stress and plenty
AM Bolt, WT Klimecki - Journal of Applied Toxicology, 2012 - Wiley Online Library
Autophagy is a critical cellular process orchestrating the lysosomal degradation of cellular
components in order to maintain cellular homeostasis and respond to cellular stress. A …
components in order to maintain cellular homeostasis and respond to cellular stress. A …
Autophagy: The spotlight for cellular stress responses
Autophagy is an essential cellular mechanism which plays “housekeeping” role in normal
physiological processes including removing of long lived, aggregated and misfolded …
physiological processes including removing of long lived, aggregated and misfolded …
Oncosuppressive functions of autophagy
Macroautophagy (herein referred to as autophagy) constitutes a phylogenetically old
mechanism leading to the lysosomal degradation of cytoplasmic structures. At baseline …
mechanism leading to the lysosomal degradation of cytoplasmic structures. At baseline …
Regulation of autophagy in oxygen-dependent cellular stress
SW Ryter, A MK Choi - Current pharmaceutical design, 2013 - ingentaconnect.com
Oxidative stress caused by supraphysiological production of reactive oxygen species (ROS),
can cause cellular injury associated with protein and lipid oxidation, DNA damage, and …
can cause cellular injury associated with protein and lipid oxidation, DNA damage, and …
Toxic metals and autophagy
S Chatterjee, S Sarkar… - Chemical research in …, 2014 - ACS Publications
The earth's resources are finite, and it can no longer be considered a source of
inexhaustible bounty for the human population. However, this realization has not been able …
inexhaustible bounty for the human population. However, this realization has not been able …
Autophagy regulation and integration with cell signaling
A Hamacher-Brady - Antioxidants & redox signaling, 2012 - liebertpub.com
Significance: Study over the past decade has revealed the critical role of autophagy in
homeostatic and stress cell signaling. Autophagy is an intracellular process whereby double …
homeostatic and stress cell signaling. Autophagy is an intracellular process whereby double …
Autophagy: cellular and molecular mechanisms
D Glick, S Barth, KF Macleod - The Journal of pathology, 2010 - Wiley Online Library
Autophagy is a self‐degradative process that is important for balancing sources of energy at
critical times in development and in response to nutrient stress. Autophagy also plays a …
critical times in development and in response to nutrient stress. Autophagy also plays a …