Last few decades unveiled the existence of diverse pool of non-coding RNAs, small RNAs,
and repetitive elements which can play a pivotal role in maintaining the cellular homeostasis …

Molecular genetics insight into the pathogenesis of several neurodegenerative diseases,
such as Alzheimer׳ s disease, Parkinson׳ s disease, Huntington׳ s disease and amyotrophic …

Recently, manipulation of gene expression and switching genes on or off highlight the
potential of nucleic acid-based therapies (NA-BTs). Alzheimer's Disease (AD) is a common …

The post-genomic era has unveiled the existence of a large repertory of non-coding RNAs
and repetitive elements that play a fundamental role in cellular homeostasis and …

Most neurodegenerative disorders afflict the ageing population and are often incurable.
Therefore, therapeutic development is a major focus in biomedical research. We highlight a …

The complexity of the central nervous system (CNS) exposes it to a number of different
diseases, often caused by only small variations in gene sequence or expression level …

Therapeutics that directly target RNAs are promising for a broad spectrum of disorders,
including the neurodegenerative diseases. This is exemplified by the FDA approval of …

Oligonucleotide therapeutics are emerging as a promising class of therapeutics in various
areas of human health. In the long run, oligonucleotides are likely to become a major class …

MicroRNAs (miRNAs) are a key gene regulator and play essential roles in several biological
and pathological mechanisms in the human system. In recent years, plenty of miRNAs have …

Nucleic acid-based technologies have received significant interest in recent years as novel
theranostic strategies for various diseases. The approval by the United States Food and …