The measurement of Pavlovian forms of fear extinction offers a relatively simple behavioral
preparation that is nonetheless tractable, from a translational perspective, as an approach to …

Fear extinction, the reduction of fear by repeated exposure to the object of fear, is a crucial
paradigm of inhibitory learning and the acknowledged preclinical model for behavior …

Laboratory models of extinction learning in animals and humans have the potential to
illuminate methods for improving clinical treatment of fear-based clinical disorders. However …

Whereas fear memories are rapidly acquired and enduring over time, extinction memories
are slow to form and are susceptible to disruption. Consequently, behavioral therapies that …

Although exposure to major psychological trauma is unfortunately common, risk for related
neuropsychiatric conditions, such as post-traumatic stress disorder (PTSD), varies greatly …

Remembering and forgetting are fundamental features of an organism. Extinction is a type of
forgetting where there is a decrease in the significance and/or the meaning of an associative …

Fear extinction is the decrease in conditioned fear responses that normally occurs when a
conditioned stimulus (CS) is repeatedly presented in the absence of the aversive …

The neural circuitry underlying the fear response is extremely well conserved across
mammalian species, which has allowed for the rapid translation of research findings in …

Current exposure-based therapies aimed to reduce pathological fear and anxiety are now
amongst the most effective interventions for trauma and anxiety related disorders …

Therapeutic interventions for disorders of fear and anxiety rely on behavioral approaches
that reduce pathological fear memories. For example, learning that threat-predictive stimuli …