Well-Defined Bifunctional Dendrimer Bearing 54 Nitric Oxide-Releasing Moieties and 54 Ursodeoxycholic Acid Groups Presenting High Anti-Inflammatory Activity

AM Garzon-Porras, DL Bertuzzi, K Lucas… - … Science & Engineering, 2022 - ACS Publications
Nitric oxide (NO) and ursodeoxycholic acid (UDCA) are endogenous molecules involved in
physiological processes associated with inflammation. Since inflammatory processes are …

Nitric oxide releasing polyamide dendrimer with anti-inflammatory activity

AM Garzon-Porras, DL Bertuzzi, K Lucas… - ACS Applied Polymer …, 2020 - ACS Publications
Inflammatory processes are related to a wide variety of diseases with high global impact.
Nitric oxide (NO) is an excellent candidate for the treatment of such diseases due to its …

Dendrimers as antiinflammatory prodrugs

M Tabarzad, F Ghorbani-Bidkorbeh… - Dendrimer-Based …, 2021 - Elsevier
Dendrimer prodrugs are highly branched polymeric nanostructures bearing special
therapeutic agents through covalent bound. Controlled size and fine polydispersity, good …

Dendrimers as a scaffold for nitric oxide release

NA Stasko, MH Schoenfisch - Journal of the American Chemical …, 2006 - ACS Publications
The preparation and characterization of nitric oxide (NO)-releasing dendrimer conjugates
are reported. Generation 3 and 5 polypropylenimine dendrimers (DAB-Am-16 and DAB-Am …

Nitric oxide releasing-dendrimers: an overview

AC Roveda Júnior, DW Franco - Brazilian Journal of Pharmaceutical …, 2013 - SciELO Brasil
Platforms able to storage, release or scavenge NO in a controlled and specific manner is
interesting for biological applications. Among the possible matrices for these purposes …

Anti-inflammatory activity of polyamide dendrimers bearing bile acid termini synthesized via SPAAC

AM Garzón-Porras, DL Bertuzzi, K Lucas… - Journal of Nanoparticle …, 2019 - Springer
Inflammation is a general pathomechanism associated with numerous diseases of global
impact such as many cancers, metabolic disorders, and neurodegenerative and …

Structurally diverse nitric oxide-releasing poly (propylene imine) dendrimers

Y Lu, B Sun, C Li, MH Schoenfisch - Chemistry of Materials, 2011 - ACS Publications
Structurally diverse secondary amine-functionalized poly (propylene imine)(PPI) dendrimers
capable of tunable nitric oxide (NO) release were synthesized in a straightforward, one-step …

Anti‐Inflammatory Properties of Dendrimers per se

M Hayder, S Fruchon, JJ Fournié… - The Scientific World …, 2011 - Wiley Online Library
Dendrimers are polybranched and polyfunctionalized tree‐like polymers. Unlike linear
polymers, they have perfectly defined structure and molecular weight, due to their iterative …

Dendrimers as anti-inflammatory agents

PK Avti, A Kakkar - Brazilian Journal of Pharmaceutical Sciences, 2013 - SciELO Brasil
Dendrimers constitute an intriguing class of macromolecules which find applications in a
variety of areas including biology. These hyperbranched macromolecules with tailored …

Structure-activity characterization of nitric oxide-releasing dendrimers as dual-action antibacterial agents

BV Worley - 2016 - search.proquest.com
The increasing prevalence of antibiotic-resistant bacteria coupled with the inherent
resistance of biofilm-based infections have necessitated the development of new …