Lipid metabolism in oncology: why it matters, how to research, and how to treat

Y Matsushita, H Nakagawa, K Koike - Cancers, 2021 - mdpi.com
Simple Summary Metabolic reprogramming is gaining attentions as a hallmark of cancers.
However, lipid metabolism has been difficult to analyze due to technical problems. In recent …

Lipid metabolism in cancer progression and therapeutic strategies

Y Fu, T Zou, X Shen, PJ Nelson, J Li, C Wu, J Yang… - MedComm, 2021 - Wiley Online Library
Dysregulated lipid metabolism represents an important metabolic alteration in cancer. Fatty
acids, cholesterol, and phospholipid are the three most prevalent lipids that act as energy …

The lipid metabolic landscape of cancers and new therapeutic perspectives

W Wang, L Bai, W Li, J Cui - Frontiers in oncology, 2020 - frontiersin.org
Lipid metabolism reprograming, as a hallmark of malignancy, has received renewed interest
in recent years in such areas as energy sources, cell membrane components, and signaling …

Greasing the wheels of the cancer machine: the role of lipid metabolism in cancer

MT Snaebjornsson, S Janaki-Raman, A Schulze - Cell metabolism, 2020 - cell.com
Altered lipid metabolism is among the most prominent metabolic alterations in cancer.
Enhanced synthesis or uptake of lipids contributes to rapid cancer cell growth and tumor …

The heterogeneity of lipid metabolism in cancer

JK Park, NJ Coffey, A Limoges, A Le - The heterogeneity of cancer …, 2018 - Springer
The study of cancer cell metabolism has traditionally focused on glycolysis and
glutaminolysis. However, lipidomic technologies have matured considerably over the last …

[HTML][HTML] New dawn for cancer cell death: emerging role of lipid metabolism

C Zhang, N Zhu, H Li, Y Gong, J Gu, Y Shi, D Liao… - Molecular …, 2022 - Elsevier
Background Resistance to cell death, a protective mechanism for removing damaged cells,
is a “Hallmark of Cancer” that is essential for cancer progression. Increasing attention to …

Targeting lipid metabolism in cancer metastasis

G Pascual, B Majem, SA Benitah - … et Biophysica Acta (BBA)-Reviews on …, 2024 - Elsevier
This review delves into the most recent research on the metabolic adaptability of cancer
cells and examines how their metabolic functions can impact their progression into …

Lipid metabolic reprogramming in tumor microenvironment: from mechanisms to therapeutics

HR Jin, J Wang, ZJ Wang, MJ Xi, BH Xia… - Journal of Hematology & …, 2023 - Springer
Lipid metabolic reprogramming is an emerging hallmark of cancer. In order to sustain
uncontrolled proliferation and survive in unfavorable environments that lack oxygen and …

[HTML][HTML] Lipid metabolism and cancer

X Bian, R Liu, Y Meng, D Xing, D Xu, Z Lu - Journal of Experimental …, 2021 - rupress.org
Dysregulation in lipid metabolism is among the most prominent metabolic alterations in
cancer. Cancer cells harness lipid metabolism to obtain energy, components for biological …

Lipids in the tumor microenvironment: From cancer progression to treatment

KC Corn, MKA Windham, M Rafat - Progress in lipid research, 2020 - Elsevier
Over the past decade, the study of metabolic abnormalities in cancer cells has risen
dramatically. Cancer cells can thrive in challenging environments, be it the hypoxic and …